Date published: 2026-6-1

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Lymphocyte Marker Activators

The chemical class known as Lymphocyte Marker Activators refers to a diverse group of molecules or compounds that have the ability to influence or modulate the expression, activation, or function of specific markers or surface molecules on lymphocytes. Lymphocytes are a critical subset of white blood cells that play a central role in the adaptive immune response, and they can be further classified into B cells, T cells, and natural killer (NK) cells. These cells express a multitude of cell surface markers or antigens that are essential for their identification, activation, and communication within the immune system. Lymphocyte marker activators can exert their effects on these markers, potentially impacting various aspects of lymphocyte biology.

The expression and activation of lymphocyte markers are crucial for the proper functioning of the immune system. For example, the CD3 marker is essential for the activation of T cells, while CD19 is a B cell marker that plays a role in B cell receptor signaling. CD56 is an NK cell marker involved in their cytotoxic activity. Activators of lymphocyte markers can modulate the immune response by influencing the interactions between lymphocytes and other immune cells, such as antigen-presenting cells or target cells. Understanding the mechanisms by which these activators affect lymphocyte markers is of great interest in immunology research, as it can shed light on the regulation of immune responses and may have implications for various areas of immunological study, including infectious diseases, cancer immunotherapy, and autoimmune disorders.

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA is known to activate protein kinase C, which can lead to the activation and proliferation of lymphocytes, potentially increasing the expression of lymphocyte markers.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

As a calcium ionophore, ionomycin can increase intracellular calcium levels, which may enhance lymphocyte activation and marker expression.

Concanavalin A

11028-71-0sc-203007
sc-203007A
sc-203007B
50 mg
250 mg
1 g
$119.00
$364.00
$947.00
17
(2)

This plant lectin can bind to certain sugar molecules on lymphocytes, stimulating cell division and possibly the expression of lymphocyte markers.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$63.00
$92.00
$250.00
$485.00
$1035.00
$2141.00
69
(5)

Although it is immunosuppressive, cyclosporin A can affect the expression of lymphocyte activation markers.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid influences immune cell development and might alter lymphocyte marker expression.