Concanavalin A (CAS 11028-71-0)
See product citations (17)
Alternate Names:
ConA
Application:
Concanavalin A is a compound that induces apoptosis
CAS Number:
11028-71-0
Purity:
≥76% (lymphocyte transfer rate)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts. It serves as a powerful tool for biochemists and physiologists in exploring the structure and function of biological molecules. The protein interacts with carbohydrates, enabling researchers to investigate the interactions between carbohydrates and proteins. Concanavalin A has been instrumental in studying the structure and function of carbohydrates, proteins, and other biological molecules, providing a way to examine their structural characteristics and interactions.
Concanavalin A (CAS 11028-71-0) References
- Concanavalin A aggregation and toxicity on cell cultures. | Vetri, V., et al. 2010. Biochim Biophys Acta. 1804: 173-83. PMID: 19782769
- Concanavalin A, from an old protein to novel candidate anti-neoplastic drug. | Li, CY., et al. 2010. Curr Mol Pharmacol. 3: 123-8. PMID: 20533895
- Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics. | Li, WW., et al. 2011. Biochem Biophys Res Commun. 414: 282-6. PMID: 21951850
- A triazatruxene-based glycocluster as a fluorescent sensor for concanavalin A. | Wang, KR., et al. 2013. Chemistry. 19: 2903-9. PMID: 23307316
- Concanavalin A-polysaccharides binding affinity analysis using a quartz crystal microbalance. | Coulibaly, FS. and Youan, BB. 2014. Biosens Bioelectron. 59: 404-11. PMID: 24768820
- Preparation of Concanavalin A-Chelating Magnetic Nanoparticles for Selective Enrichment of Glycoproteins. | Dong, L., et al. 2015. Anal Chem. 87: 6849-53. PMID: 26066908
- Heterometal-Coordinated Monomeric Concanavalin A at pH 7.5 from Canavalia ensiformis. | Chung, NJ., et al. 2017. J Microbiol Biotechnol. 27: 2241-2244. PMID: 29025256
- Structural and biochemical analyses of concanavalin A circular permutation by jack bean asparaginyl endopeptidase. | Nonis, SG., et al. 2021. Plant Cell. 33: 2794-2811. PMID: 34235541
- Concanavalin A differentiates gram-positive bacteria through hierarchized nanostructured transducer. | da Silva Junior, AG., et al. 2021. Microbiol Res. 251: 126834. PMID: 34364021
- Preparation of optimized concanavalin A-conjugated Dynabeads® magnetic beads for CUT&Tag. | Fujiwara, Y., et al. 2021. PLoS One. 16: e0259846. PMID: 34784358
- Concanavalin A: coordination diversity to xenobiotic metal ions and biological consequences. | Jang, H., et al. 2021. Dalton Trans. 50: 17817-17831. PMID: 34806716
- Concanavalin A as a promising lectin-based anti-cancer agent: the molecular mechanisms and therapeutic potential. | Huldani, H., et al. 2022. Cell Commun Signal. 20: 167. PMID: 36289525
- New Insight into the Concanavalin A-Induced Apoptosis in Hepatocyte of an Animal Model: Possible Involvement of Caspase-Independent Pathway. | Zhao, X., et al. 2023. Molecules. 28: PMID: 36770978
- Induction of apoptosis and tyrosine phosphorylation of cellular proteins in T cells and non-T cells by stimulation with concanavalin A. | Nagase, F., et al. 1998. Microbiol Immunol. 42: 567-74. PMID: 9776398
- Role of mitochondrial membrane potential in concanavalin A-induced apoptosis in human fibroblasts. | Kulkarni, GV., et al. 1998. Exp Cell Res. 245: 170-8. PMID: 9828113
Inhibitor of:
Amisyn, AMPD3, Clathrin LCA, EAT-4, FAM69A, FLJ37512, GABAC Rρ1, GNS, Hrnbp3, LRRTM2, LRTM2, MPP4, MPPED2, NKAIN2, Oct-3A, Olfr1010, Olfr1076, Olfr3, Olfr340, Olfr342, OR10H5, OR2AT4, OR2D3, OR2T27, OR4D1, OR4N5, OR5H15, OR5K2, PRX VI, rhophilin, Rim1, Sg V, SH3TC2, SLC38A6, Synaptoporin, Synaptotagmin XIII, Vmn2r110, Vmn2r118, Vmn2r31, Vmn2r33, Vmn2r36, ZNF609, and ZNF622.Activator of:
ADAM22, C2, C3d, C6, C8α, C8β, CD137, CD27L, CD3-η, CD4, CD8β, CRTAM, CTBS, Ear12, Endoglycosidase, Esgp, Factor V, Follicular DC Marker, FXYD7, GIMAP3, gp91phox, granzyme, granzyme C, granzyme E, granzyme G, granzyme M, H2-Kb, H60a, HYAL3, ICOS, IFN-γ, IgG κ light chain, IgG λ light chain, IL-1Rrp2, IL-2, IL-2R, Influenza A ns1, Integrin αIIb, KCNMB2, KLRI1, LIMP I, LMP2, LPAP, Ly-6A/E, Lymphocyte Marker, MAN1A1, Mast Cell Tryptase, MHC class II, Ox40, Proteassemblin, SAV1, Sectm1a, SLP-76, SUSD4, Syntaxin, T Cell Marker, T-cell receptor Vδ 2, TAGAP1, TCR α, TCR V α 8, TCR V β, TPSB2, Trav3n-3, Tryptase, VAX1, vCCI, and WC1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Concanavalin A, 50 mg | sc-203007 | 50 mg | $119.00 | |||
Concanavalin A, 250 mg | sc-203007A | 250 mg | $364.00 | |||
Concanavalin A, 1 g | sc-203007B | 1 g | $947.00 |