The Lymphocyte Antigen 6 Complex, Locus A/E (Ly-6A/E, also known as Sca-1) is a protein that has been used as a stem cell marker and is involved in regulating cell activation and proliferation. There are no direct chemical activators for Ly-6A/E. However, several compounds may indirectly influence Ly-6A/E's function through associated pathways or cellular processes. Ly-6A/E Activators represent a class of chemicals that can influence the function of Ly-6A/E. These compounds can indirectly influence the function of Ly-6A/E through their effects on related cellular pathways.
Chemicals such as Concanavalin A, PMA, Ionomycin, Cyclosporine A, LPS, IL-2, IL-7, IFN-γ, TNF-α, IL-1β, IL-6, and IL-10 can potentially influence Ly-6A/E function through their effects on Ly-6A/E-related pathways. The effects of these chemicals on Ly-6A/E function are context-dependent and may vary based on the cellular environment and other biochemical parameters.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Concanavalin A | 11028-71-0 | sc-203007 sc-203007A sc-203007B | 50 mg 250 mg 1 g | $119.00 $364.00 $947.00 | 17 | |
Concanavalin A is a lectin that can increase the expression of Ly-6A/E by stimulating T cell activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC) which can influence T cell activation, potentially affecting Ly-6A/E expression. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin is a calcium ionophore which can increase intracellular calcium levels, leading to T cell activation and potentially increased Ly-6A/E expression. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Cyclosporine A is an immunosuppressive drug that can inhibit T cell activation, potentially influencing Ly-6A/E expression. | ||||||