LSP1 Inhibitors
LSP1 is involved in the regulation of cell motility and the organization of the cytoskeleton, particularly in hematopoietic cells. The compounds listed above target various aspects of cytoskeletal dynamics and signaling pathways that can affect cell movement and structure. By altering the polymerization and depolymerization of actin, or by modulating the signaling pathways that govern these processes, these compounds could, in theory, affect the function of LSP1 within cells.
The chemical class that might be considered as indirect LSP1 inhibitors would include actin dynamics modulators, kinase inhibitors, and other compounds that target signaling molecules involved in the regulation of the cytoskeleton. They could potentially influence LSP1's function by modifying the actin cytoskeleton, disrupting actin binding, or altering the signaling pathways that regulate these processes. However, the effects of such compounds would likely be broad and influence a wide variety of cellular functions, not just those associated with LSP1.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
An inhibitor of actin polymerization that can disrupt F-actin formation and potentially affect LSP1's role in the cytoskeleton. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
A toxin that binds to monomeric G-actin, preventing its polymerization to F-actin and thus could influence LSP1-associated actin dynamics. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
A cyclic peptide that stabilizes F-actin and may alter the dynamics of actin polymerization and depolymerization, thereby affecting LSP1 function. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that could affect actomyosin contractility and thereby influence the cellular processes where LSP1 is involved. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
An inhibitor of myosin light chain kinase (MLCK) that may affect cell motility and cytoskeletal dynamics, potentially altering LSP1's function. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $315.00 $1020.00 | 5 | |
An inhibitor of the Arp2/3 complex that can suppress actin nucleation, potentially affecting LSP1's role in actin branching and networking. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $48.00 $122.00 $432.00 $812.00 | 4 | |
An inhibitor of the neuronal Wiskott-Aldrich syndrome protein (N-WASP), which controls actin polymerization, potentially influencing LSP1 function. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
An inhibitor of myosin II that can reduce cell contraction and motility, potentially affecting pathways related to LSP1. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
A formin homology 2 domain (FH2) inhibitor that can disrupt actin nucleation and elongation, potentially influencing LSP1-associated actin dynamics. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $88.00 $311.00 | 17 | |
A protein kinase C inhibitor that could alter signal transduction pathways and potentially impact the function of LSP1 in cells. | ||||||