LRRTM2 Activators
LRRTM2 is intrinsically linked to synaptic dynamics and functionality. TIts chemical activators, ranging from BDNF to Nimodipine, represent a diverse array of compounds known to influence synaptic signaling. Targeting ionotropic receptors with compounds such as D-cycloserine, which acts on NMDA receptors, and Picrotoxin, a GABA_A receptor antagonist, provides an avenue for adjusting the excitatory/inhibitory balance within neural circuits.
The ion channels and receptors, being fundamental components of synaptic sites, are further modulated by chemicals like CNQX, an antagonist for AMPA/Kainate receptors. Each of these agents offers a distinct method of influencing synaptic transmission and by extension, the associated proteins like LRRTM2. Lastly, engaging with metabotropic signaling using MPEP, an mGluR5 antagonist, underscores the comprehensive modulation of synaptic dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates cellular cAMP levels, modulating synaptic plasticity. | ||||||
D-Cycloserine | 68-41-7 | sc-221470 sc-221470A sc-221470B sc-221470C | 200 mg 1 g 5 g 25 g | $28.00 $77.00 $142.00 $530.00 | 4 | |
Acts on NMDA receptors, which play roles in synaptic plasticity. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
L-type calcium channel blocker; calcium signaling is pivotal in synapses. | ||||||
Picrotoxin | 124-87-8 | sc-202765 sc-202765A sc-202765B | 1 g 5 g 25 g | $67.00 $286.00 $1326.00 | 11 | |
GABA_A receptor antagonist, influencing excitatory/inhibitory balance in synapses. | ||||||
6-Cyano-7-nitroquinoxaline-2,3-dione | 115066-14-3 | sc-505104 | 10 mg | $208.00 | 2 | |
AMPA/Kainate receptor antagonist, affecting glutamatergic synaptic transmission. | ||||||
Aniracetam | 72432-10-1 | sc-203514 sc-203514A | 50 mg 250 mg | $115.00 $456.00 | ||
Modulates AMPA receptors, influencing synaptic transmission. | ||||||
(±)-Baclofen | 1134-47-0 | sc-200464 sc-200464A | 1 g 5 g | $56.00 $258.00 | ||
GABA_B receptor agonist, modulating inhibitory synaptic transmission. | ||||||
MPEP hydrochloride | 96206-92-7 | sc-279454A sc-279454 | 10 mg 50 mg | $136.00 $520.00 | ||
mGluR5 antagonist, which can modulate metabotropic glutamate signaling in synapses. | ||||||
Nimodipine | 66085-59-4 | sc-201464 sc-201464A | 100 mg 1 g | $61.00 $307.00 | 2 | |
Another L-type calcium channel blocker influencing calcium-dependent synaptic processes. | ||||||