LRRC10B Activators
LRRC10B activators, as gleaned from general cellular signaling pathways, comprise chemicals known to influence integral pathways and cellular functions. Forskolin, through its capability to boost cAMP levels, can activate PKA, a kinase that has a vast role in cell modulation, potentially influencing proteins like LRRC10B. Concurrently, PMA can stimulate Protein kinase C (PKC), a kinase implicated in diverse cellular operations, thereby potentially impacting LRRC10B. Calcium, a pivotal second messenger, governs numerous cellular functions. Chemicals such as Ionomycin, which raises intracellular calcium, and BAPTA-AM, which serves as a calcium chelator, can influence calcium-mediated cellular activities and proteins.
Moreover, understanding that protein kinases play central roles in cellular signal transduction, molecules like Genistein, which inhibits tyrosine kinases, and KN-93, a CaMKII inhibitor, might affect proteins that are downstream or associated with these kinases, potentially including LRRC10B. Similarly, influencing broader pathways like MAPK with PD98059 or PI3K with LY294002 provides potential avenues to modulate cellular processes and proteins that might be intertwined with the role or function of LRRC10B.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin elevates cAMP levels by activating adenylyl cyclase. Elevated cAMP can activate PKA which, through downstream targets, may lead to the activation or increased expression of LRRC10B. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA directly activates PKC, leading to the phosphorylation of downstream proteins. This can alter cellular functions that might lead to an enhanced activity or expression of LRRC10B. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin raises intracellular calcium levels, activating calcium-dependent proteins. The calcium signaling can cascade to possibly enhance LRRC10B's activity or expression. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
As a cAMP analog, 8-Br-cAMP activates PKA. The activation of PKA can modulate downstream targets, potentially influencing LRRC10B's activity. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
By chelating calcium, BAPTA-AM affects calcium-mediated signaling. The resulting changes in calcium-dependent pathways might alter the activity or expression of LRRC10B. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram inhibits PDE4, causing an increase in cAMP levels. Elevated cAMP activates PKA, which through its action on downstream proteins might lead to the activation of LRRC10B. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein's inhibition of tyrosine kinases can disrupt multiple signaling pathways. This disruption can alter the cellular environment, potentially leading to the activation of LRRC10B. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
KN-93 inhibits CaMKII, affecting calcium-mediated signaling. Changes in this pathway might cascade effects leading to altered LRRC10B activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 elevates intracellular calcium levels. The increase in calcium signaling can activate calcium-dependent pathways, potentially influencing LRRC10B's activity or expression. | ||||||