LOC730128 Inhibitors
LY294002 and wortmannin, both phosphoinositide 3-kinase inhibitors, disrupt PI3K-dependent signaling cascades that can modulate a wide range of cellular functions, possibly including those associated with LOC730128. Rapamycin, an mTOR inhibitor, plays a pivotal role in cell growth and proliferation, which can indirectly influence the activity of various proteins, including LOC730128. Cycloheximide, by inhibiting protein synthesis, can affect the overall protein composition within the cell, including that of LOC730128. MG132 prevents the degradation of proteins, leading to an accumulation that may disrupt normal cellular functions, potentially affecting proteins regulated by or regulating LOC730128.
Other compounds such as SB203580, U0126, PD98059, and SP600125 target specific kinases involved in MAPK signaling pathways, which are crucial in controlling cell division, differentiation, and response to stress, all of which may have implications for LOC730128 activity. Brefeldin A disrupts protein trafficking, which could impact the subcellular localization and function of LOC730128. Lastly, okadaic acid, a protein phosphatase inhibitor, can lead to increased phosphorylation of cellular proteins, potentially affecting those that interact with or regulate LOC730128.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A kinase inhibitor that can disrupt protein phosphorylation, potentially altering LOC730128 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A phosphoinositide 3-kinases inhibitor which can affect downstream signaling, possibly influencing LOC730128 function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor which can alter cell growth and proliferation processes, affecting proteins like LOC730128 indirectly. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis which can reduce the overall levels of LOC730128 in the cell. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can increase the cellular levels of proteins, potentially including LOC730128, leading to dysregulation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAP kinase inhibitor which may affect the protein's function or expression if LOC730128 is part of this pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
An inhibitor of MEK1/2 which can prevent activation of the ERK pathway, possibly affecting LOC730128. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that can alter signal transduction pathways, potentially affecting LOC730128. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein transport by inhibiting the exchange of GDP for GTP, possibly affecting LOC730128 localization and function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Specifically inhibits MEK, which could alter ERK pathway signaling, potentially affecting LOC730128. | ||||||