Kinase inhibitors like PD98059 and U0126 that target MEK to prevent the activation of the ERK pathway, to PI3K inhibitors like LY294002 and Wortmannin that disrupt AKT signaling. JNK inhibitor SP600125 and p38 MAPK inhibitor SB203580 target the MAPK signaling pathway, which is integral to many cellular functions including proliferation, differentiation, and stress responses.
Other members of this class include mTOR inhibitor Rapamycin, which affects cell growth and proliferation, and Bortezomib, a proteasome inhibitor that influences protein degradation pathways. Trichostatin A, a histone deacetylase inhibitor, alters gene expression patterns, potentially affecting the expression of LOC729801. Similarly, Thapsigargin, a SERCA inhibitor, disrupts calcium homeostasis, which can have wide-ranging effects on cellular functions that may involve LOC729801. QNZ can affect the transcription of a multitude of genes, potentially including those related to LOC729801. Lastly, Cyclosporin A acts on T-cell activation and other immune responses, which could indirectly influence LOC729801's activity or expression.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which could reduce ERK pathway signaling potentially affecting LOC729801 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, potentially altering AKT signaling and thereby influencing LOC729801-related processes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, potentially modulating AP-1 activity which may alter LOC729801 function. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor, might alter stress response pathways potentially linked to LOC729801. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
MEK inhibitor that can affect ERK pathway signaling, potentially modulating LOC729801 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor which can affect cell growth and proliferation pathways related to LOC729801. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor, could disrupt AKT pathway signaling potentially influencing LOC729801. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor, can affect protein degradation pathways potentially related to LOC729801. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor, can alter gene expression potentially affecting LOC729801. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
SERCA inhibitor, can disrupt calcium homeostasis which may influence LOC729801-related activities. | ||||||