LOC644193 Inhibitors
LOC644193 inhibitors such as Wortmannin and LY294002, which target the PI3K signaling axis, a central hub in cellular communication that could be involved in regulating LOC644193. U0126 and PD0325901 are representatives that inhibit the MEK1/2 enzymes, thereby impacting the MAPK/ERK pathway which may play a crucial role in determining the activity or expression of LOC644193.
The inhibitors also include SB203580, which targets p38 MAPK, and Dasatinib, which targets a broad spectrum of tyrosine kinases, both of which are involved in pathways that can intersect with LOC644193 regulation. Thapsigargin and KN-93 disrupt calcium signaling, a ubiquitous cellular messaging system, which might impact LOC644193 function. 2-Deoxy-D-glucose serves to inhibit glycolysis, thereby affecting cellular energy balance and potentially LOC644193 activity as a consequence of altered metabolic states. Cyclopamine inhibits Hedgehog signaling, an essential pathway for cellular differentiation and development, which may affect the context within which LOC644193 operates. ZM-447439, by inhibiting Aurora kinases, can alter cell cycle progression and, hence, the regulation of LOC644193 during cell division. Finally, Y-27632 targets the Rho-associated protein kinase (ROCK), influencing cytoskeletal dynamics and potentially affecting the cellular infrastructure surrounding LOC644193.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor, which can disrupt signaling pathways that might regulate LOC644193 activity or expression. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, which can alter stress response pathways that intersect with LOC644193 regulation. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
A tyrosine kinase inhibitor, potentially affecting signaling cascades that could regulate LOC644193. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), affecting calcium signaling that might influence LOC644193. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor, which can alter cellular metabolism and potentially modulate LOC644193 activity due to changes in cellular energy balance. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor, altering signaling that can be relevant to LOC644193 regulation. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
An inhibitor of the Hedgehog signaling pathway, which can affect cell fate and possibly the role of LOC644193 in development or disease. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
An Aurora kinase inhibitor, which can disrupt cell cycle progression and potentially influence the regulation of LOC644193 during cell division. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
An inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII), with the potential to affect calcium signaling pathways that regulate LOC644193. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
An inhibitor of Rho-associated protein kinase (ROCK), which can modulate cytoskeletal dynamics and potentially influence LOC644193's cellular context. | ||||||