LOC643677 Activators
CCDC168, as suggested by the name, includes this coiled-coil configuration, which is indicative of its potential role in a multitude of cellular processes including vesicular transport, cell division, transcriptional regulation, and the maintenance of cytoskeletal structure. The exact biological function of CCDC168, however, remains elusive and subject to ongoing research.
The significance of coiled-coil domains lies in their ability to mediate the formation of protein complexes, which is a fundamental aspect of cellular machinery. They enable the stable association of proteins with one another to carry out complex tasks within the cell. For example, they are prominent in the structure of motor proteins, vesicle tethering complexes, and in the assembly of multiprotein structures such as the centrosome and spindle apparatus during cell division.Given the widespread involvement of coiled-coil domains in essential cellular functions, mutations or disruptions in proteins like CCDC168 could have profound implications for cellular homeostasis and may be implicated in human diseases. In this context, CCDC168 might be a candidate for further investigation in studies of diseases that involve protein aggregation or misfolding, as well as those affecting cellular infrastructure and dynamics.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine disrupts microtubule dynamics, potentially affecting proteins with coiled-coil domains involved in cellular structure and transport. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules and could influence proteins with coiled-coil domains by altering cellular architecture. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
This agent disrupts microtubule polymerization and could affect proteins with coiled-coil domains that interact with the cytoskeleton. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
A cAMP analog that activates protein kinase A (PKA), potentially affecting proteins with coiled-coil domains. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), potentially phosphorylating various proteins, including those with coiled-coil domains. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor affecting protein turnover, potentially influencing the stability and function of proteins with coiled-coil domains. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin affects multiple signaling pathways and could influence proteins with coiled-coil domains. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Activating sirtuins, resveratrol might influence proteins involved in chromatin remodeling and metabolic regulation, potentially including those with coiled-coil domains. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences the Wnt/beta-catenin pathway and might affect proteins with coiled-coil domains. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a key regulator of cell growth and proliferation, possibly affecting proteins with coiled-coil domains. | ||||||