LOC642574 Inhibitors
IQANK1 is involved in calcium signaling pathways due to its IQ motif, this protein could play a role in a wide array of cellular activities, including muscle contraction, neurotransmitter release, cell growth, and gene expression. Its interaction with calmodulin could be calcium-dependent, allowing IQANK1 to act as a molecular switch that transduces calcium signals to effect cellular changes.
The presence of an ankyrin repeat suggests that IQANK1 may have a structural role, providing a scaffold for the assembly of multiprotein complexes at the cell membrane or within the cell. This could mean that IQANK1 is involved in organizing clusters of proteins necessary for signal transduction pathways or for maintaining cellular architecture. Given the nature of IQANK1, it's conceivable that this protein could be involved in neurological function, given that both calcium signaling and protein scaffolding are critical in neuronal communication and plasticity. Dysregulation of such a protein could potentially be linked to neurological disorders, where impaired calcium signaling and synaptic dysfunction are common features.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calmidazolium chloride | 57265-65-3 | sc-201494 sc-201494A | 10 mg 50 mg | $156.00 $612.00 | 27 | |
An inhibitor of calmodulin, which interacts with IQ motifs in calcium signaling pathways. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
A specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII), potentially affecting proteins with IQ motifs. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An immunosuppressant that inhibits calcineurin, affecting calcium signaling pathways relevant to IQ motif-containing proteins. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A broad-spectrum kinase inhibitor, potentially affecting pathways involving protein-protein interactions. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor, affecting protein degradation pathways, relevant for proteins with ankyrin repeats. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MAP kinase kinase (MEK), potentially influencing signaling pathways involving ankyrin repeat proteins. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, which might affect signaling pathways relevant to ankyrin repeat-containing proteins. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, affecting cytoskeletal dynamics, potentially relevant to proteins with ankyrin repeats. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, potentially influencing protein synthesis and cell growth pathways, which may intersect with IQANK1 functions. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
A SERCA pump inhibitor, impacting calcium homeostasis, potentially relevant to IQ motif-containing proteins. | ||||||