LOC400958 inhibitors belong to a specialized chemical class designed to selectively target and modulate the function of the non-coding RNA LOC400958. Classified as a long intergenic non-protein coding RNA (lincRNA), LOC400958 lacks the capacity to code for proteins but has garnered attention as an essential player in the intricate network of non-coding RNA-mediated cellular regulation. The inhibitors developed for LOC400958 are intricately designed to interact with the specific molecular structure of this RNA, aiming to disrupt its normal interactions within the cellular environment and potentially influence various cellular regulatory pathways.
The molecular architecture of LOC400958 inhibitors is precisely tailored to engage specific binding sites on the RNA molecule, inducing changes in its conformation and dynamics. In laboratory research, these inhibitors serve as indispensable tools, enabling scientists to investigate the nuanced functions of LOC400958 in various cellular contexts. By selectively inhibiting LOC400958, researchers aim to unravel the complex mechanisms of non-coding RNA-mediated regulation, contributing to a deeper understanding of the intricate network of molecular players orchestrating cellular processes and potential roles in cellular homeostasis. The study of LOC400958 inhibitors stands at the forefront of advancing our comprehension of non-coding RNA biology and the nuanced roles these molecules play in the intricate web of cellular regulatory mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
It binds to and inhibits RNA polymerase II, thereby inhibiting the transcription of RNA, including lincRNAs. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $62.00 $108.00 $210.00 | 1 | |
A nucleoside analog that can inhibit inosine monophosphate dehydrogenase, potentially affecting RNA synthesis. | ||||||
Tiazofurin | 60084-10-8 | sc-475805 | 5 mg | $440.00 | ||
Inhibits inosine monophosphate dehydrogenase, leading to a depletion of guanine nucleotides and affecting RNA synthesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
A nucleoside analog similar to adenosine, it can terminate RNA chain extension due to the absence of a hydroxyl group at the 3' end. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Inhibits inosine monophosphate dehydrogenase, potentially decreasing RNA and DNA synthesis. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Folate analog that inhibits dihydrofolate reductase, affecting nucleotide synthesis and thus RNA transcription. | ||||||
Folinic Acid | 58-05-9 | sc-337846A sc-337846B sc-337846 | 5 mg 25 mg 100 mg | $110.00 $291.00 $592.00 | ||
Acts as a rescue agent for normal cells during high-dose methotrexate therapy, but may also influence RNA synthesis indirectly. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A nucleoside analog of cytidine that can be incorporated into RNA, affecting its function and stability. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Intercalates into DNA and inhibits RNA synthesis by preventing the elongation step of RNA polymerase. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA polymerase II by blocking the phosphorylation of the C-terminal domain of the largest subunit. | ||||||