LOC390738 Inhibitors
Staurosporine is a broad-spectrum kinase inhibitor, targeting multiple kinases which may phosphorylate or otherwise modulate LOC390738. Thapsigargin and Cyclosporin A can disrupt calcium signaling, which is a vital secondary messenger in numerous cellular processes, potentially including those in which LOC390738 is implicated. Glycolysis and protein glycosylation are vital for cellular metabolism and protein maturation; inhibitors like 2-Deoxy-D-glucose and Tunicamycin can affect these processes, thereby impacting proteins such as LOC390738. Brefeldin A and Chloroquine interfere with protein trafficking and endosomal function, which can be crucial for the proper localization and function of LOC390738.
The modulation of second messenger systems through inhibition by compounds like U73122 can prevent downstream signaling effects, possibly affecting LOC390738's signaling roles. Okadaic Acid's inhibition of phosphatases can lead to changes in phosphorylation states within the cell, affecting numerous signaling cascades and potentially LOC390738's activity. LY294002 and PD98059 target key components in the PI3K/Akt and MAPK/ERK pathways, respectively, which are central to cell survival, proliferation, and differentiation. Lastly, Rapamycin inhibits mTOR, a central regulator of cell growth and protein synthesis, which can influence the expression and function of LOC390738.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can inhibit a wide range of kinases which may interact with LOC390738. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
A SERCA pump inhibitor that can increase cytosolic calcium levels, possibly affecting LOC390738 activity. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that can inhibit calcineurin, potentially altering LOC390738's role in signaling. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor that can alter energy metabolism, potentially impacting LOC390738 functions. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
An N-linked glycosylation inhibitor that can disrupt proper folding and function of glycoproteins, possibly including LOC390738. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
An inhibitor of protein transport from the endoplasmic reticulum to the Golgi apparatus, possibly affecting LOC390738 trafficking. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
A compound that can raise endosomal pH, potentially interfering with LOC390738's endosomal function. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
A potent inhibitor of protein phosphatases 1 and 2A, which can alter multiple signaling pathways that may involve LOC390738. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can alter the PI3K/Akt signaling pathway, potentially affecting LOC390738 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MEK, which is involved in the MAPK/ERK pathway, potentially influencing LOC390738's role in this pathway. | ||||||