Date published: 2026-5-16

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LOC198437 Activators

LKAAEAR motif-containing 1, abbreviated as LKAAEAR1, is a protein whose encoding gene has not been extensively characterized in the scientific literature. The protein's name suggests that it contains a specific amino acid sequence, the LKAAEAR motif, which could be critical for its function. This motif could be involved in protein-protein interactions, signaling pathways, or other cellular processes.Motifs in proteins are often short, conserved sequences of amino acids that are functionally and structurally significant. They can serve as sites for interaction with other molecules or as recognition elements by other proteins. The presence of the LKAAEAR motif in LKAAEAR1 implies that it may play a role in binding to other proteins or possibly nucleic acids, contributing to the regulation of various cellular functions such as gene expression, signal transduction, or enzymatic activity.

Although the detailed biological role of LKAAEAR1 remains to be elucidated, proteins with similar motifs are known to be involved in diverse cellular activities. They can act as scaffolds that bring together multiple protein complexes, influence the activity of enzymes, or participate in the structural organization of protein assemblies.Given that motifs can also dictate the localization of proteins within different cellular compartments, LKAAEAR1 might have a specific subcellular distribution that is crucial for its function. Understanding where LKAAEAR1 localizes within the cell could provide insights into its role and interactions with other cellular components.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA is a potent activator of protein kinase C (PKC), which can phosphorylate various proteins and potentially influence those with the LKAAEAR motif.

8-Bromo-cAMP

76939-46-3sc-201564
sc-201564A
10 mg
50 mg
$126.00
$328.00
30
(1)

This cAMP analog can activate PKA and potentially affect proteins with the LKAAEAR motif through phosphorylation.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin activates the insulin receptor and its signaling pathways, potentially affecting proteins with the LKAAEAR motif.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AICAR activates AMPK, a kinase that may influence proteins with the LKAAEAR motif through phosphorylation.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin has multiple effects on cellular signaling and might influence proteins with the LKAAEAR motif.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

As an activator of sirtuins, resveratrol might influence proteins involved in metabolic regulation, potentially including those with the LKAAEAR motif.

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

Metformin activates AMPK, which could potentially influence proteins with the LKAAEAR motif.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin inhibits mTOR, a key regulator of cell growth and proliferation, and may affect proteins with the LKAAEAR motif.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium influences the Wnt/beta-catenin pathway and might affect proteins with the LKAAEAR motif.