LOC143666 inhibitors constitute a specific chemical class designed to selectively target and modulate the function of the non-coding RNA LOC143666. LOC143666, also known as long intergenic non-protein coding RNA 143666, is a member of the vast family of non-coding RNAs that play diverse roles in cellular processes, despite not encoding proteins themselves. The inhibitors developed for LOC143666 are intricately designed to interact with the specific molecular structure of this non-coding RNA, with the aim of disrupting its normal interactions within the cellular milieu and potentially influencing regulatory mechanisms at the RNA level.
The molecular architecture of LOC143666 inhibitors is precisely tailored to engage specific binding sites on the RNA molecule, inducing changes in its conformation and dynamics. This interaction holds the potential to impact the regulatory roles that LOC143666 may play in cellular processes, contributing to a nuanced understanding of non-coding RNA function. In laboratory research, these inhibitors serve as essential tools, allowing scientists to dissect the intricate functions of LOC143666 in various cellular contexts. By manipulating the function of LOC143666, researchers aim to unravel the complex mechanisms of RNA-mediated regulation, shedding light on the broader implications for cellular processes and potential roles in cellular homeostasis. The study of LOC143666 inhibitors stands at the forefront of advancing our understanding of non-coding RNA biology and the potential functional roles these molecules play in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Intercalates into DNA and prevents RNA synthesis by inhibiting RNA polymerase, potentially reducing gene expression globally. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $66.00 $101.00 $143.00 | 85 | |
Forms DNA adducts and cross-links DNA strands, which can inhibit DNA replication and transcription. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $84.00 $306.00 $1104.00 | 30 | |
Inhibits DNA polymerase, particularly in eukaryotic cells, which can suppress DNA replication and indirectly affect gene expression. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Binds to bacterial RNA polymerase and inhibits RNA synthesis; in eukaryotic cells, it may also inhibit mitochondrial RNA polymerase. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Inhibits DNA topoisomerase I, leading to DNA damage and potentially affecting gene expression and cell cycle progression. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Targets DNA topoisomerase II, leading to DNA strand breaks and potentially disrupting gene transcription. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II transcription elongation, which could reduce mRNA synthesis of many genes. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Specifically inhibits RNA polymerase II in eukaryotic cells, leading to a decrease in mRNA synthesis and potentially reduced protein expression. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
May modulate various signaling pathways and affect transcription factors, potentially altering gene expression profiles. | ||||||
Acetazolamide | 59-66-5 | sc-214461 sc-214461A sc-214461B sc-214461C sc-214461D sc-214461E sc-214461F | 10 g 25 g 100 g 250 g 500 g 1 kg 2 kg | $81.00 $177.00 $434.00 $541.00 $883.00 $1479.00 $2244.00 | 1 | |
Although mainly an inhibitor of carbonic anhydrase, it can alter cellular pH and indirectly affect gene expression. | ||||||