LOC100041465 Inhibitors
LOC100041465 may have inhibitors like Staurosporine and Dasatinib are broad-spectrum kinase inhibitors, targeting multiple kinases that could phosphorylate and activate LOC100041465, thereby leading to a decrease in its functional activity. Bafilomycin A1 and Geldanamycin disrupt cellular homeostasis by interfering with lysosomal acidification and protein folding, respectively, which can affect the degradation and stability of the target protein. U0126 and Cyclosporin A are specific inhibitors of MEK and calcineurin, potentially altering the phosphorylation status of LOC100041465, while 2-Deoxy-D-glucose and Metformin affect cellular metabolism, which can lead to changes in the energy-dependent regulatory mechanisms of the protein.
Compounds such as Ivermectin and Alisertib impact ion channel activity and cell division, respectively, and can alter cellular states that indirectly modulate the function or expression of LOC100041465. Omipalisib's dual inhibition of PI3K and mTOR can suppress major signaling pathways that regulate protein synthesis, potentially leading to reduced expression of LOC100041465. Lastly, ABT-199, being a Bcl-2 inhibitor, induces apoptosis in cells, which can result in the overall reduction of protein levels, including that of LOC100041465, if it is implicated in cell survival.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can block the activity of a wide range of kinases, potentially reducing phosphorylation events that activate LOC100041465. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
A V-ATPase inhibitor that can disrupt lysosomal acidification, potentially affecting the degradation pathway of LOC100041465 if it undergoes lysosomal degradation. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that can inhibit calcineurin, potentially affecting the dephosphorylation and activity of LOC100041465 if it is regulated by calcineurin. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor that can reduce ATP levels, potentially affecting the energy-dependent processes regulating LOC100041465. | ||||||
Ivermectin | 70288-86-7 | sc-203609 sc-203609A | 100 mg 1 g | $56.00 $75.00 | 2 | |
An ion channel inhibitor that can alter cell membrane potential, potentially affecting the cellular processes that modulate LOC100041465. | ||||||
MLN8237 | 1028486-01-2 | sc-394162 | 5 mg | $220.00 | ||
An Aurora kinase inhibitor that can disrupt cell division, potentially affecting LOC100041465 if its expression is cell cycle-dependent. | ||||||
GSK2126458 | 1086062-66-9 | sc-364503 sc-364503A | 2 mg 10 mg | $260.00 $1029.00 | ||
A dual PI3K/mTOR inhibitor that can suppress the PI3K/AKT/mTOR pathway, potentially affecting the synthesis and turnover of LOC100041465. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
An Hsp90 inhibitor that can disrupt protein folding, potentially leading to misfolded LOC100041465 and its subsequent degradation. | ||||||
ABT-199 | 1257044-40-8 | sc-472284 sc-472284A sc-472284B sc-472284C sc-472284D | 1 mg 5 mg 10 mg 100 mg 3 g | $116.00 $330.00 $510.00 $816.00 $1632.00 | 10 | |
A Bcl-2 inhibitor that can induce apoptosis, potentially decreasing the levels of LOC100041465 if it is overexpressed in survival pathways. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
A Src family kinase inhibitor that can interfere with multiple signaling pathways, potentially affecting the activity or expression of LOC100041465. | ||||||