LOC100041418 Inhibitors
LOC100041418 inhibitors may include Staurosporine and LY294002, target kinases and PI3K respectively, which are pivotal regulators of cell signaling. Their inhibitory effects can alter the phosphorylation status of a suite of proteins, potentially including LOC100041418, thereby modulating its activity. U0126 and SB203580 specifically inhibit the MEK and p38 MAP kinase pathways, which are integral to cell proliferation, differentiation, and stress responses. MG132 and bortezomib target the proteasome, a complex responsible for protein degradation, thus potentially influencing the turnover of LOC100041418.
SP600125, rapamycin, and nilotinib each target different kinases (JNK, mTOR, and BCR-ABL respectively), which are involved in cell survival, growth, and differentiation signaling pathways. The effects of these inhibitors can create an environment that affects the functional role of LOC100041418. 5-Azacytidine and vorinostat alter gene expression patterns by affecting epigenetic marks, which can lead to changes in the levels of proteins such as LOC100041418. Finally, ibrutinib's inhibition of Bruton's tyrosine kinase can impact B-cell receptor signaling, potentially affecting any immunological role that LOC100041418 may play.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can inhibit a broad spectrum of kinases, potentially affecting signaling pathways LOC100041418 may be involved in. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, which can block the PI3K/AKT signaling pathway, potentially affecting the activity or regulation of LOC100041418 if it interacts with this pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAP kinase inhibitor, which can alter inflammatory responses and cell differentiation processes that LOC100041418 may be part of. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can prevent the degradation of proteins, potentially affecting the levels and function of LOC100041418. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, which can modulate apoptosis and other cellular processes LOC100041418 may be involved in. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor which can affect cell growth and proliferation, potentially impacting the function of LOC100041418 if it is part of the mTOR pathway. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that can lead to the accumulation of regulatory proteins, potentially influencing LOC100041418 activity or stability. | ||||||
Nilotinib | 641571-10-0 | sc-202245 sc-202245A | 10 mg 25 mg | $205.00 $405.00 | 9 | |
A tyrosine kinase inhibitor, which can inhibit BCR-ABL and other kinases, potentially altering signaling pathways involving LOC100041418. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can change gene expression patterns, potentially affecting the expression of LOC100041418. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase inhibitor that can alter chromatin structure and gene expression, potentially impacting LOC100041418. | ||||||