Assuming "LIN-35" refers to a protein or gene that is integral to a particular biological process, activators of LIN-35 would be molecules that enhance its biological activity. These activators could potentially work by binding directly to the LIN-35 protein, inducing a conformational change that results in increased activity, or by facilitating its interaction with other proteins or substrates. The chemical structures of LIN-35 activators would likely be diverse, as they would need to possess specific characteristics that enable them to interact with distinct structural motifs or domains within LIN-35. These characteristics could include particular arrangements of atoms, charged groups, hydrophobic or hydrophilic elements, or even larger molecular frameworks for protein-protein interaction modulation.
In the realm of research, scientists investigating LIN-35 activators would employ a variety of techniques to understand the interaction between these molecules and the LIN-35 protein. Studies might include computational modeling to predict how these activators could bind to the protein and what effects they may exert on its structure and function. Experimental approaches would likely involve the use of in vitro assays to assess the biochemical consequences of activator binding, such as changes in the enzymatic activity of LIN-35 or alterations in its ability to interact with other cellular components. Advanced analytical techniques like mass spectrometry, circular dichroism, and fluorescence spectroscopy could provide insights into the binding dynamics and structural changes. Furthermore, if the precise structure of the LIN-35 protein were known, techniques such as X-ray crystallography or cryo-electron microscopy might be used to solve the structure of the protein in complex with activator molecules, giving a clear picture of the molecular interactions at play. This could elucidate the mechanism by which these activators enhance LIN-35 activity. Nonetheless, without concrete scientific evidence to define "LIN-35 Activators," this discussion remains purely theoretical and is not grounded in any known chemical classification.
| 製品名 | CAS # | カタログ # | 数量 | 価格 | 引用文献 | レーティング |
|---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
ヒドロキシ尿素はDNA損傷を誘発し、細胞周期制御タンパク質に影響を与え、ストレス反応の一部としてLIN-35の発現を変化させる可能性がある。 | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
カンプトテシンは、トポイソメラーゼIを阻害することによってDNA損傷を誘導し、細胞応答としてLIN-35発現の変化を引き起こす可能性がある。 | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
エトポシドはトポイソメラーゼII阻害を介してDNA鎖切断を引き起こし、DNA損傷応答中のLIN-35発現に影響を与える可能性がある。 | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
ロスコビチンはサイクリン依存性キナーゼ阻害剤であり、潜在的にLIN-35を含む細胞周期制御因子に影響を与える可能性がある。 | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $82.00 $300.00 $1082.00 | 30 | |
アフィジコリンはDNAポリメラーゼ阻害剤であり、細胞周期チェックポイント活性化の一環としてLIN-35発現の変化を引き起こす可能性がある。 | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
パクリタキセルは微小管を安定化させ、細胞を有糸分裂で停止させ、その過程でLIN-35の発現に影響を与える可能性がある。 | ||||||
Thymidine | 50-89-5 | sc-296542 sc-296542A sc-296542C sc-296542D sc-296542E sc-296542B | 1 g 5 g 100 g 250 g 1 kg 25 g | $48.00 $72.00 $265.00 $449.00 $1724.00 $112.00 | 16 | |
チミジンは、高濃度で使用されるとS期における細胞周期のブロックを引き起こし、LIN-35の発現に影響を与える可能性がある。 | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
メトトレキサートはジヒドロ葉酸還元酵素を阻害し、S期停止に導くが、これはLIN-35のような細胞周期制御因子の発現に影響を与えるかもしれない。 | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
ノコダゾールは微小管の重合を阻害し、細胞周期の停止をもたらすが、これはLIN-35の発現レベルに影響を与える可能性がある。 | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
シスプラチンはDNA付加体を形成し、DNA損傷反応の活性化につながり、細胞反応の一部としてLIN-35の発現に影響を及ぼす可能性がある。 | ||||||