The LHFP protein, which stands for Lipoma HMGIC Fusion Partner, is a member of the TETRA (Transmembrane protein with EGF-like and two Follistatin-like domains) protein family. This protein family is characterized by having epidermal growth factor (EGF)-like and follistatin-like domains which are thought to be involved in cell signaling and cell-to-cell communication.LHFP is encoded by the LHFP gene and is expressed in various tissues with potential roles in cellular processes. The exact function of LHFP is not fully elucidated, but it is believed to play a role in cell adhesion and migration, processes that are crucial during development and for the maintenance of tissue architecture. The protein's structure, which includes the EGF-like and follistatin-like domains, suggests it may interact with other proteins on the cell surface to mediate these functions.
Interestingly, LHFP has also been implicated in the pathology of certain types of benign tumors, particularly lipomas, where translocations involving the LHFP gene and other genes such as HMGA2 are commonly observed. These genetic rearrangements can lead to the formation of fusion proteins that may contribute to tumor growth and development.On a molecular level, LHFP may interact with components of the extracellular matrix and with cell surface receptors, potentially influencing signal transduction pathways that regulate cellular dynamics. However, the precise molecular pathways and interaction partners of LHFP remain to be fully characterized.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor, potentially altering DNA methylation patterns and impacting LHFP function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, affecting chromatin remodeling and gene expression, possibly influencing LHFP. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Influences histone acetylation, potentially affecting the expression of genes including LHFP. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Acts as a histone deacetylase inhibitor, which might influence LHFP gene expression patterns. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates various cellular pathways, potentially impacting LHFP through epigenetic changes. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Affects gene expression, potentially influencing pathways related to LHFP. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, could affect cellular processes relevant to LHFP's function. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences Wnt signaling, potentially intersecting with pathways involving LHFP. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, might impact gene expression relevant to LHFP. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Affects multiple signaling pathways, possibly impacting LHFP. | ||||||