LETM2 Activators
n general, LETM proteins, with "LETM1" being the most characterized among them, are known to be involved in mitochondrial function. The acronym LETM stands for "Leucine Zipper-EF-hand containing Transmembrane." LETM1, for instance, is an integral mitochondrial inner membrane protein that has been implicated in the regulation of mitochondrial volume and ion homeostasis, specifically in the transport of K+ and H+ ions. Mutations in LETM1 have been associated with Wolf-Hirschhorn syndrome, a genetic disorder that affects many parts of the body.
If "LETM2" were a protein with a function similar to LETM1, it might also be assumed to play a role in mitochondrial physiology, possibly in ion transport or energy metabolism. Proteins that are part of ion transport systems are critical for maintaining the electrochemical gradients across mitochondrial membranes, which are essential for ATP synthesis through oxidative phosphorylation.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Affects mitochondrial function and calcium homeostasis, potentially influencing LETM2 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, indirectly impacts mitochondrial dynamics and function, possibly affecting LETM2. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
Inhibits glycolysis, impacting energy metabolism and potentially mitochondrial function related to LETM2. | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $58.00 | 2 | |
Uncouples oxidative phosphorylation in mitochondria, potentially impacting LETM2 function. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
Targets mitochondrial oxidative damage, could indirectly influence LETM2. | ||||||
Valinomycin | 2001-95-8 | sc-200991 | 25 mg | $163.00 | 3 | |
A potassium ionophore, affecting mitochondrial ion balance, potentially impacting LETM2. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
Inhibits ATP synthase in mitochondria, affecting mitochondrial function, potentially relevant to LETM2. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
A protonophore uncoupling agent in mitochondria, could influence LETM2-related processes. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
Inhibits mitochondrial electron transport chain, potentially affecting LETM2 function. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
Inhibits mitochondrial complex III, impacting mitochondrial function, possibly relevant to LETM2. | ||||||