n general, LETM proteins, with "LETM1" being the most characterized among them, are known to be involved in mitochondrial function. The acronym LETM stands for "Leucine Zipper-EF-hand containing Transmembrane." LETM1, for instance, is an integral mitochondrial inner membrane protein that has been implicated in the regulation of mitochondrial volume and ion homeostasis, specifically in the transport of K+ and H+ ions. Mutations in LETM1 have been associated with Wolf-Hirschhorn syndrome, a genetic disorder that affects many parts of the body.
If "LETM2" were a protein with a function similar to LETM1, it might also be assumed to play a role in mitochondrial physiology, possibly in ion transport or energy metabolism. Proteins that are part of ion transport systems are critical for maintaining the electrochemical gradients across mitochondrial membranes, which are essential for ATP synthesis through oxidative phosphorylation.
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产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
影响线粒体功能和钙平衡,可能影响 LETM2 的活性。 | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
一种 mTOR 抑制剂,间接影响线粒体动力学和功能,可能会影响 LETM2。 | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
抑制糖酵解,影响能量代谢,并可能影响与 LETM2 有关的线粒体功能。 | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $58.00 | 2 | |
解偶联线粒体中的氧化磷酸化,可能影响 LETM2 的功能。 | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
针对线粒体氧化损伤,可间接影响 LETM2。 | ||||||
Valinomycin | 2001-95-8 | sc-200991 | 25 mg | $163.00 | 3 | |
一种钾离子拮抗剂,会影响线粒体的离子平衡,从而可能影响 LETM2。 | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
抑制线粒体中的 ATP 合酶,影响线粒体功能,可能与 LETM2 有关。 | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
线粒体中的质子胨解偶联剂,可能会影响 LETM2 的相关过程。 | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
抑制线粒体电子传递链,可能影响 LETM2 的功能。 | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
抑制线粒体复合物 III,影响线粒体功能,可能与 LETM2 有关。 |