Date published: 2026-4-30

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LDOC1 Inhibitors

LDOC1 inhibitors represent a class of chemical compounds designed to modulate the activity of LDOC1, which stands for Leucine Zipper Downregulated. LDOC1 is a protein that has garnered attention in the realm of cancer research due to its potential involvement in cellular processes associated with tumor development and progression. The development of LDOC1 inhibitors primarily aims to elucidate its molecular functions and its role within the complex network of signaling pathways.

In the context of LDOC1 inhibition, researchers typically explore various strategies to interfere with its activity. One approach involves the design and screening of small molecule inhibitors that can specifically target LDOC1. These inhibitors may function by binding to LDOC1 and disrupting its interactions with other proteins or cellular components, thereby modulating its role in cellular processes relevant to cancer. Additionally, researchers may explore the use of gene-silencing techniques, such as RNA interference (RNAi) or CRISPR-Cas9 gene editing, to downregulate the expression of LDOC1 at the genetic level. This approach effectively inhibits the production of LDOC1 within cancer cells, potentially altering their behavior and response to signaling cues. Monoclonal antibodies may also be developed to target and neutralize LDOC1, stopping its interactions with other molecules and affecting downstream signaling events. Overall, the study of LDOC1 inhibitors contributes to a deeper understanding of the complex molecular mechanisms underlying cancer biology and provides insights into potential strategies for further research in the field.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

MDV3100

915087-33-1sc-364354
sc-364354A
5 mg
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7
(1)

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Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$63.00
$114.00
$218.00
$349.00
74
(2)

Gefitinib is a tyrosine kinase inhibitor targeting EGFR (epidermal growth factor receptor) to inhibit the growth of cancer cells in various solid tumors, particularly in non-small cell lung cancer.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Sorafenib is a multikinase inhibitor that suppresses tumor cell proliferation and angiogenesis by targeting several kinases involved in cancer growth, including VEGFR and RAF kinases.

Imatinib mesylate

220127-57-1sc-202180
sc-202180A
25 mg
100 mg
$45.00
$111.00
61
(1)

Imatinib is a tyrosine kinase inhibitor that selectively inhibits the BCR-ABL fusion protein, preventing its signaling and used for chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs).

Erlotinib, Free Base

183321-74-6sc-396113
sc-396113A
sc-396113B
sc-396113C
sc-396113D
500 mg
1 g
5 g
10 g
100 g
$87.00
$135.00
$293.00
$505.00
$3827.00
42
(0)

Erlotinib is a small molecule inhibitor of EGFR, inhibiting the tyrosine kinase activity of EGFR, which is overactive in some cancer types, leading to cell growth inhibition.

Lapatinib

231277-92-2sc-353658
100 mg
$420.00
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(1)

Lapatinib inhibits both EGFR and HER2/neu receptor tyrosine kinases, used for HER2-positive breast cancer by blocking the signaling pathways that promote cancer cell growth.

Abemaciclib

1231929-97-7sc-507342
10 mg
$110.00
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Abemaciclib is another CDK 4/6 inhibitor that prevents cell cycle progression in cancer cells, used in various cancer types including breast cancer.

Vandetanib

443913-73-3sc-220364
sc-220364A
5 mg
50 mg
$167.00
$1353.00
(1)

Vandetanib inhibits several kinases, including VEGFR, EGFR, and RET, leading to the suppression of angiogenesis and tumor cell growth, used in thyroid cancer therapy.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

Dasatinib is a tyrosine kinase inhibitor that targets multiple kinases, including BCR-ABL and Src kinases, studied in the research of chronic myeloid leukemia (CML) and other malignancies.