LDLRAD2 activators belong to a chemical class of compounds designed to interact with and modulate the activity of the LDLRAD2 protein. LDLRAD2, also known as Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 2, is a relatively newly identified protein that is a member of the low-density lipoprotein receptor (LDLR) family. While the exact functions of LDLRAD2 are still under investigation, it is believed to play roles in cellular processes related to lipid metabolism, endocytosis, and potentially cell signaling. The presence of class A LDL receptor domains suggests potential involvement in the uptake and clearance of lipoproteins or other ligands, similar to other members of the LDL receptor family. The designation activators implies that compounds within this class interact with LDLRAD2 to modulate its activity, potentially leading to downstream effects on lipid metabolism and cellular processes.
Investigations into LDLRAD2 activators involve elucidating the molecular mechanisms underlying their interaction with the LDLRAD2 protein and how this interaction impacts cellular processes. Understanding the pharmacological properties of these compounds is crucial for deciphering how they affect LDLRAD2 activity and potentially influence lipid metabolism, endocytosis, and cellular signaling. By unraveling the biological functions and regulatory mechanisms of LDLRAD2, researchers aim to deepen our understanding of cellular physiology and may uncover novel insights into the molecular pathways underlying lipid metabolism and related diseases. Continued exploration of LDLRAD2 activators holds promise for advancing our knowledge of lipid biology and may provide insights into new strategies for manipulating cellular function in experimental contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $30.00 $87.00 $132.00 $434.00 | 13 | |
As inhibitors of HMG-CoA reductase, statins lower cholesterol synthesis and might upregulate LDLRAD2 as part of a compensatory mechanism to increase cholesterol uptake. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fibrates activate PPARα and can influence lipid metabolism, potentially affecting the expression of genes involved in LDL processing and transport, including LDLRAD2. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $70.00 $416.00 $3060.00 $5610.00 $145.00 | 10 | |
A retinoid that can activate RXR receptors, involved in various metabolic pathways, potentially influencing the expression of genes like LDLRAD2. | ||||||
25-Hydroxycholesterol | 2140-46-7 | sc-214091B sc-214091 sc-214091A sc-214091C | 5 mg 10 mg 25 mg 100 mg | $52.00 $89.00 $166.00 $465.00 | 8 | |
As an oxysterol involved in cholesterol homeostasis, 25-hydroxycholesterol might modulate the expression of genes related to lipid metabolism, including LDLRAD2. | ||||||
Cholic acid | 81-25-4 | sc-255020 sc-255020A sc-255020B sc-255020C sc-255020D | 25 g 100 g 500 g 1 kg 5 kg | $48.00 $121.00 $567.00 $998.00 $4480.00 | 11 | |
Bile acids can signal through nuclear receptors like FXR, potentially influencing the expression of genes involved in lipid metabolism, including LDLRAD2. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin regulates lipid metabolism and could potentially influence the expression of genes like LDLRAD2 in pathways related to lipid uptake and storage. | ||||||
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $40.00 $75.00 $150.00 | ||
Thyroid hormones influence metabolism and could potentially regulate the expression of genes involved in lipid metabolism, including LDLRAD2. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Involved in various metabolic processes, Vitamin D3 might influence the expression of genes related to lipid metabolism, including LDLRAD2. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
As a PPARγ agonist, pioglitazone influences lipid and glucose homeostasis, potentially affecting the expression of genes like LDLRAD2. | ||||||
Ezetimibe | 163222-33-1 | sc-205690 sc-205690A | 25 mg 100 mg | $94.00 $236.00 | 12 | |
By inhibiting intestinal cholesterol absorption, ezetimibe might influence hepatic cholesterol metabolism and potentially the expression of genes like LDLRAD2. | ||||||