LBH Activators
LBH (Limb Bud and Heart Development) activators represent a specialized class of chemical compounds that are designed to modulate the expression and activity of LBH, a critical gene involved in the development and patterning of limbs and the heart during embryogenesis. LBH is a transcription factor and co-regulator that plays a pivotal role in orchestrating the precise molecular events necessary for limb bud outgrowth and heart morphogenesis. These activators are meticulously crafted to interact with regulatory elements associated with the LBH gene, potentially influencing its expression and affecting the downstream genetic programs involved in limb and heart development. Mechanistically, the actions of LBH activators can involve binding to specific DNA sequences within the LBH gene promoter or enhancer regions, thereby promoting or enhancing LBH gene expression.
Research on LBH activators is essential for advancing our understanding of the intricate genetic networks governing embryonic development, particularly in the context of limb and heart formation. Scientists in this field primarily focus on elucidating the precise molecular mechanisms by which these compounds impact LBH's function and their downstream effects on gene expression patterns during development. LBH is known to interact with other key transcription factors and signaling pathways, making it a crucial node in the regulatory network controlling organogenesis. Consequently, understanding the role of LBH activators contributes to our broader knowledge of developmental biology and the intricate processes underlying limb and heart development, shedding light on the genetic and molecular basis of embryogenesis. These activators serve as invaluable tools for researchers seeking to ultimately deepen our understanding of the complex world of developmental biology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A known regulator of limb development, it might have a direct or indirect role in modulating LBH expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoid receptor agonist; might modulate LBH expression in certain cellular contexts. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Involved in various cellular processes including inflammation and differentiation; potential influence on LBH. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
GSK-3 inhibitor, involved in the Wnt/β-catenin pathway; might influence LBH expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Histone deacetylase inhibitor; potential epigenetic modulation of LBH expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates cAMP levels; might influence LBH through cAMP-dependent pathways. | ||||||
IWR-1-endo | 1127442-82-3 | sc-295215 sc-295215A | 5 mg 10 mg | $82.00 $135.00 | 19 | |
Inhibits Wnt/β-catenin signaling; could indirectly modulate LBH expression. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Rho-associated protein kinase (ROCK) inhibitor; potential influence on LBH in certain cellular contexts. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PKC activator; might influence LBH expression through protein kinase C (PKC) pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor; could influence LBH through its effects on the PI3K/Akt pathway. | ||||||