LARGE2 Activators
LARGE2 belongs to the glycosyltransferase family. Glycosyltransferases are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. LARGE2, in particular, is involved in the glycosylation of alpha-dystroglycan, a critical protein that mediates interactions between cells and the extracellular matrix. This process of glycosylation, or the attachment of sugars to proteins, is essential for a variety of biological functions.
LARGE2 Activators refer to molecules that increase the activity of the LARGE2 enzyme. By amplifying the enzyme's function, these activators would potentially augment the glycosylation of alpha-dystroglycan. LARGE2 and its activities are part of the broader study of glycosylation, a fundamental biological process. As glycosylation can significantly impact protein function, stability, and intermolecular interactions, research into enzymes like LARGE2 and potential activators is an important aspect of molecular and cellular biology. It can provide key insights into the intricate mechanisms governing cellular function and biological processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
As a PI3K inhibitor, LY294002 could potentially stimulate LARGE2 activity by modulating PI3K/Akt signaling, a key part in numerous processes including protein glycosylation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates Protein Kinase C. PKC, involved in numerous cellular processes, might stimulate the activity of glycosyltransferases like LARGE2. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin escalates cellular levels of cAMP, a secondary messenger participating in numerous cellular processes. This could potentially stimulate LARGE2 activity. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
Imatinib, a tyrosine kinase inhibitor, might hypothetically stimulate LARGE2 activity by modifying tyrosine kinase signaling, potentially influencing glycosylation processes. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187, a calcium ionophore that modulates intracellular calcium levels, could potentially stimulate LARGE2 activity by acting on various cellular processes, including glycosylation. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Sodium nitroprusside, a nitric oxide donor, might stimulate LARGE2 activity by modifying various signaling pathways that nitric oxide participates in. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a glucocorticoid, might stimulate LARGE2 activity by acting on a wide range of cellular processes, due to its anti-inflammatory and immunosuppressant effects. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
Gefitinib, an EGFR inhibitor, might stimulate LARGE2 activity by modifying EGF signaling, which could potentially influence the activity of glycosyltransferases. | ||||||