Laminin-R inhibitors are a class of small molecules or compounds that specifically target and interact with laminin receptors within the human body. Laminins are a family of large, complex proteins that are essential components of the extracellular matrix, a structural framework found in various tissues and organs throughout the body. Laminins play a crucial role in cell adhesion, migration, differentiation, and tissue organization. They form the foundation of the extracellular matrix and help maintain tissue integrity. Laminin receptors, also known as integrins, are cell surface proteins that bind to laminins, mediating cellular interactions with the extracellular matrix.
Laminin-R inhibitors are designed to modulate these interactions by interfering with the binding of laminin receptors to laminins. By doing so, they can potentially influence various cellular processes such as cell adhesion, migration, and signaling pathways. This class of inhibitors holds promise in research related to cell biology, tissue engineering, and the study of diseases characterized by aberrant cell-matrix interactions. Researchers are actively investigating the precise mechanisms and potential applications of laminin-R inhibitors, aiming to unlock their full potential for a deeper understanding of fundamental biological processes and their role in various health conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
5-Fluorouracil is a pyrimidine analog that may disrupt RNA synthesis and function, potentially reducing Laminin-R expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a polyphenolic compound found in turmeric, may modulate various signaling pathways, influencing Laminin-R expression levels. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in grapes and berries, may exhibit anti-inflammatory properties, possibly downregulating Laminin-R expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
As an isoflavone from soy, Genistein may influence estrogenic pathways, potentially altering the expression of Laminin-R. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, might modulate signaling cascades, influencing the transcriptional regulation of Laminin-R. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Sirolimus, an mTOR inhibitor, may suppress protein synthesis pathways, possibly impacting the expression of Laminin-R. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
Sorafenib, a kinase inhibitor, may inhibit multiple signaling pathways, potentially reducing Laminin-R expression. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $153.00 $938.00 | 5 | |
Sunitinib, a receptor tyrosine kinase inhibitor, might alter cellular signaling, possibly leading to decreased Laminin-R expression. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
Gefitinib, an EGFR inhibitor, might impact cellular growth pathways, potentially downregulating Laminin-R expression. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin may cause DNA damage and disrupt transcription, possibly leading to altered Laminin-R expression. | ||||||