Date published: 2025-12-18

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KRTAP19-6 Activators

Keratin Associated Protein 19-6 (KRTAP19-6) is one of the myriad of specialized proteins that play a pivotal role in the structure and integrity of hair fibers. These proteins are intimately involved in the intricate matrix that gives hair its unique combination of strength and flexibility. KRTAP19-6, like other members of the keratin-associated protein family, contributes to the formation and maintenance of the hair shaft by interacting with keratin filaments. The expression of KRTAP19-6 is a finely tuned process that occurs within the hair follicle, a dynamic mini-organ that orchestrates hair growth and cycling. Within this microenvironment, the expression of KRTAP19-6 is subject to a series of complex regulatory mechanisms that ensure its synthesis is synchronized with the hair growth cycle, and this synchronization is essential for the proper development of hair fibers with the desired qualities of resilience and texture.

The potential activators of KRTAP19-6 expression comprise a diverse array of chemicals, each capable of interfacing with cellular pathways to upregulate the production of this protein. Retinoic Acid, for instance, is known for its profound effects on skin cell differentiation and may extend these effects to the hair follicle, potentially stimulating KRTAP19-6 synthesis. Similarly, compounds like caffeine and niacinamide, commonly associated with energy metabolism and skin health, respectively, may hold the key to promoting a favorable environment for hair follicle cells to increase KRTAP19-6 production. Caffeine, for example, has been shown to prolong the active growth phase of the hair cycle, which could lead to an upsurge in KRTAP19-6 expression. On the other hand, niacinamide could enhance the cellular metabolism within hair follicles, thereby possibly boosting the production of keratin-associated proteins. Nutrient-related compounds, such as the amino acid L-Cysteine, provide the structural elements required for keratin-associated proteins, while Zinc Pyrithione and Selenium Sulfide, known for their role in maintaining scalp health, may also promote an optimal environment for the expression of KRTAP19-6. Each of these chemicals interacts with the hair follicle's microenvironment in a unique way, potentially encouraging the expression of KRTAP19-6 and contributing to the complex biological tapestry that results in healthy hair fiber formation.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid may upregulate KRTAP19-6 expression by enhancing transcriptional processes in epithelial differentiation, crucial for hair follicle development.

L-Thyroxine, free acid

51-48-9sc-207813
sc-207813A
100 mg
500 mg
$34.00
$73.00
2
(0)

L-Thyroxine could stimulate KRTAP19-6 expression by elevating basal metabolic rates, thereby promoting the growth and maturation of hair follicle cells.

Hydrocortisone

50-23-7sc-300810
5 g
$100.00
6
(1)

Hydrocortisone may increase KRTAP19-6 expression through the activation of glucocorticoid response elements within hair follicle cells during stress adaptation.

Spironolactone

52-01-7sc-204294
50 mg
$107.00
3
(1)

Spironolactone could potentially induce KRTAP19-6 expression by antagonizing androgen receptors, thus altering the hormonal environment of hair follicles.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

Caffeine may stimulate the expression of KRTAP19-6 by promoting the prolongation of the anagen phase of the hair growth cycle, encouraging cellular proliferation.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$43.00
$65.00
$200.00
$815.00
6
(1)

Nicotinamide could upregulate KRTAP19-6 by enhancing DNA repair and energy metabolism, which is essential for the active synthesis of hair keratins.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc Pyrithione might stimulate KRTAP19-6 expression through its antifungal properties, which help maintain a healthy scalp environment conducive to hair protein synthesis.

Linoleic Acid

60-33-3sc-200788
sc-200788A
sc-200788B
sc-200788C
100 mg
1 g
5 g
25 g
$33.00
$63.00
$163.00
$275.00
4
(2)

Linoleic Acid could induce KRTAP19-6 expression by maintaining the integrity of cellular membranes, supporting the structural framework necessary for keratin protein assembly.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Cholecalciferol could upregulate KRTAP19-6 by binding to the vitamin D receptor in hair follicles, which is involved in the initiation of the hair growth cycle.

L-Cysteine

52-90-4sc-286072
sc-286072A
sc-286072B
sc-286072C
sc-286072D
25 g
100 g
500 g
5 kg
10 kg
$50.00
$110.00
$440.00
$1128.00
$2135.00
1
(1)

L-Cysteine may increase KRTAP19-6 expression by supplying sulfur, a key building block for the cysteine-rich keratin proteins that contribute to hair strength.