KRTAP10 Activators

Keratin Associated Protein 10 (KRTAP10) is a protein in humans that is encoded by the KRTAP10 gene. It belongs to the keratin-associated protein (KRTAP) family, which is a group of proteins that combine with keratin to form hair and nails.Keratins are fibrous structural proteins that constitute the key structural material of hair, nails, and the outer layer of skin. KRTAPs, including KRTAP10, are small, sulfur-rich proteins that bind to keratin intermediate filaments in hair shafts, contributing to the formation of a matrix that provides hair with its strength, rigidity, and shape.

Specifically, KRTAP10 is part of the high sulfur KRTAP subgroup, characterized by a high cysteine content which forms disulfide bonds to create a rigid structure. This structure aids in the determination of the physical properties of the hair strand, such as its curliness or straightness.In summary, KRTAP10 is a keratin-associated protein that plays a crucial role in the formation and physical properties of hair. It binds to keratin intermediate filaments, contributing to the formation of a rigid structure that gives hair its strength and shape.