KRTAP10-2 Activators
KRTAP10-2, or Keratin Associated Protein 10-2, is a part of the intricate network of proteins essential for hair formation and resilience. It belongs to a larger family of keratin-associated proteins (KAPs), which play critical roles in the structure and properties of hair fibers. These proteins intermingle with keratin intermediate filaments in hair and are thought to contribute to the strength, elasticity, and robustness of hair strands. The expression of KRTAP10-2 is finely tuned and occurs primarily within the hair follicles, suggesting its expression is tightly linked to the hair growth cycle and the intricate cellular processes within the follicle. While the precise regulatory mechanisms governing KRTAP10-2 expression are complex and not yet fully understood, it is clear that its synthesis is a highly orchestrated part of hair biology.
Exploring the potential activators that could upregulate the expression of KRTAP10-2, several chemicals come to mind that could exert influence through various biological pathways. For instance, compounds like retinoic acid may increase the expression of KRTAP10-2 by promoting cell differentiation within the hair follicles. Similarly, minoxidil, a compound known to stimulate hair growth, could also enhance KRTAP10-2 levels indirectly through its vasodilatory effects, which may bolster follicular health and protein synthesis. Nutritional elements such as biotin and vitamin D are also potential upregulators, since they are vital for metabolic processes in hair follicle cells and may thus support the production of keratin-associated proteins. Furthermore, anti-inflammatory substances like eicosapentaenoic acid could potentially encourage KRTAP10-2 expression by creating a more conducive environment for hair growth and follicle health. These activators, among others, represent a diverse array of molecules that could influence the expression of hair-specific structural proteins, offering a glimpse into the complexity of hair biology and the possible biochemical pathways that could be involved in the regulation of proteins like KRTAP10-2.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid might upregulate KRTAP10-2 by enhancing cellular differentiation and proliferation in hair follicles, leading to increased synthesis of hair-specific structural proteins. | ||||||
Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $68.00 $344.00 | ||
Minoxidil could potentially stimulate KRTAP10-2 expression by expanding blood vessels and opening potassium channels, thereby promoting hair follicle health and stimulating hair growth phases that demand structural protein synthesis. | ||||||
L-Thyroxine, free acid | 51-48-9 | sc-207813 sc-207813A | 100 mg 500 mg | $34.00 $73.00 | 2 | |
L-Thyroxine may increase KRTAP10-2 expression by accelerating metabolic processes in hair follicle cells, thereby necessitating a greater production of structural proteins to sustain enhanced hair fiber production. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc Pyrithione might stimulate KRTAP10-2 by its antifungal properties, improving scalp health and potentially leading to a scalp environment that favours the synthesis of hair structural proteins. | ||||||
D-(+)-Biotin | 58-85-5 | sc-204706 sc-204706A sc-204706B | 1 g 5 g 25 g | $40.00 $105.00 $326.00 | 1 | |
Biotin, as a coenzyme for carboxylase enzymes, may enhance KRTAP10-2 expression by optimizing the energy metabolism in hair follicle cells, which could promote the synthesis of keratin-associated proteins. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Cholecalciferol might upregulate KRTAP10-2 by binding to vitamin D receptors in hair follicles, prompting the expression of genes involved in hair cycle progression, including those coding for structural proteins. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $102.00 $423.00 | ||
EPA could stimulate KRTAP10-2 expression by reducing inflammation around the hair follicles, which may enhance the conditions for the growth phase of hair that requires a robust production of keratin-based proteins. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine might promote KRTAP10-2 expression by counteracting hair follicle miniaturization and extending the anagen phase, which is associated with the active synthesis of hair structural proteins. | ||||||
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $100.00 | 6 | |
While Hydrocortisone is typically associated with hair loss at high levels, physiological levels might stimulate KRTAP10-2 expression as part of the body’s response to mild stress, which can sometimes result in transiently increased hair growth. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid could upregulate KRTAP10-2 by protecting hair follicle cells from oxidative stress, thereby potentially enhancing the cellular mechanisms that underlie the production of hair structural proteins. | ||||||