KLK11 Activators
KLK11 Activators comprise a class of chemicals that possess the potential to indirectly influence the activity of KLK11, also known as Kallikrein-related peptidase 11 or hK11. KLK11 is a serine protease involved in various physiological processes.
These chemicals encompass a diverse group, including Dibutyryl cAMP, Trichostatin A (TSA), Retinoic Acid, Epidermal Growth Factor (EGF), Prostaglandin E2 (PGE2), Dexamethasone, Phorbol Myristate Acetate (PMA), Forskolin, Thrombin, and Ionomycin. For example, Dibutyryl cAMP can activate intracellular signaling pathways like cAMP-dependent protein kinase (PKA), potentially leading to the activation of proteases like KLK11. TSA, as a histone deacetylase (HDAC) inhibitor, can indirectly influence KLK11 expression by modulating chromatin structure. Retinoic Acid influences KLK11 through nuclear receptor signaling, while EGF activates receptor-mediated pathways that can indirectly impact KLK11 in specific cellular contexts. These chemicals contribute to our understanding of the intricate regulatory networks governing KLK11 activity in various physiological and pathological conditions.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl cAMP can potentially activate KLK11 by influencing intracellular signaling pathways, such as cAMP-dependent protein kinase (PKA), which may lead to the activation of proteases like KLK11. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA is a histone deacetylase (HDAC) inhibitor that can indirectly affect KLK11 expression by modulating chromatin structure, potentially leading to altered KLK11 levels. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can influence KLK11 expression and activity through nuclear receptor signaling, potentially affecting its proteolytic function. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 can modulate KLK11 expression through intracellular signaling pathways related to inflammation and tissue remodeling. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a glucocorticoid that can potentially influence KLK11 expression, especially in the context of anti-inflammatory responses. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA can activate protein kinase C (PKC), which may indirectly impact KLK11 expression or activity through cellular signaling pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin can increase intracellular cAMP levels, potentially activating PKA and indirectly influencing KLK11 activity. | ||||||
Thrombin from human plasma | 9002-04-4 | sc-471713 | 100 U | $235.00 | ||
Thrombin can activate protease-activated receptors (PARs), which may indirectly impact KLK11 activity through cellular signaling cascades. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin can affect intracellular calcium levels, potentially influencing KLK11 activity, as calcium is a cofactor for many protease enzymes. | ||||||