KIF2C Activators are chemical compounds understood to modulate the activity or expression of KIF2C, a protein essential for proper cellular function, specifically known for its role in microtubule dynamics. Within this chemical class, compounds such as Paclitaxel and Taxol work by stabilizing microtubules, thereby influencing KIF2C's functionality related to microtubule depolymerization. Nocodazole and Vinblastine, in contrast, disrupt microtubule dynamics and formation respectively, altering the cellular environment in which KIF2C operates. Colchicine and Combretastatin, by binding to tubulin, modify microtubule structures and may subsequently impact the role of KIF2C in cellular processes.
Other chemicals in this classification, like Vincristine and Epothilone B, also engage with microtubule-related pathways by inhibiting microtubule assembly and stabilizing microtubules, respectively, thus having an impact on KIF2C activity. Monastrol, a known kinesin inhibitor, affects KIF2C by interacting with kinesin-related pathways, and 2-Methoxyestradiol, by inhibiting microtubule formation, impacts the cellular dynamics involving KIF2C. Lastly, Albendazole and Mebendazole, by disrupting and altering microtubule structures and dynamics, respectively, play roles in influencing the functionality of KIF2C within cells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Taxol stabilizes microtubules and might affect KIF2C function by altering microtubule dynamics. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubule dynamics, which could influence KIF2C activity by impacting its cellular role. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine binds to tubulin, potentially affecting KIF2C by modifying microtubule structures. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Vinblastine disrupts microtubule formation, which may alter KIF2C's function and activity. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Epothilone B stabilizes microtubules, potentially affecting the activity of KIF2C by impacting its role in microtubule dynamics. | ||||||
Combrestatin A4 | 117048-59-6 | sc-204697 sc-204697A | 1 mg 5 mg | $46.00 $81.00 | ||
Combretastatin binds to tubulin and may influence KIF2C activity by modifying microtubule structures. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Monastrol is a kinesin inhibitor and might affect KIF2C function by influencing kinesin-related pathways. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $71.00 $288.00 | 6 | |
2-Methoxyestradiol inhibits microtubule formation, which could affect the activity of KIF2C. | ||||||
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $213.00 | 1 | |
Albendazole disrupts microtubule structure, potentially influencing KIF2C functionality. | ||||||
Mebendazole | 31431-39-7 | sc-204798 sc-204798A | 5 g 25 g | $46.00 $89.00 | 2 | |
Mebendazole alters microtubule dynamics, potentially affecting KIF2C's activity in cells. | ||||||