KIAA1467 activators encompass a range of compounds that, through their interaction with various signaling pathways, can indirectly enhance the functional activity of KIAA1467. For instance, forskolin, by elevating cAMP levels, enhances PKA activity, which can indirectly influence KIAA1467's activity within the cellular context. Similarly, compounds like EGF and PMA target specific receptors or enzymes (EGFR and PKC, respectively) and initiate a cascade of events in signaling pathways that intersect with KIAA1467's role. This indirect activation illustrates the interconnected nature of cellular signaling and the for cross-talk between pathways, which can ultimately lead to the activation of KIAA1467.
Further, LY294002, U0126, and SB203580, which target PI3K, MEK, and p38 MAPK, respectively, demonstrate how modulating one pathway can impact others. The inhibition of these key enzymes in prominent signaling pathways can lead to compensatory mechanisms or shifts in cellular signaling dynamics that enhance KIAA1467 activity. This indirect activation via modulation of related pathways underscores the complexity of cellular signaling networks and the for diverse chemical compounds to influence KIAA1467.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels. Elevated cAMP can enhance PKA activity, which may influence pathways intersecting with KIAA1467, leading to its functional activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates Protein Kinase C (PKC), which is involved in numerous signaling pathways. PKC activation can indirectly influence KIAA1467 activity through interconnected signaling networks. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. By modulating p38 MAPK activity, it can influence pathways that intersect with or regulate KIAA1467, leading to its enhanced activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin increases intracellular calcium levels, which can activate various signaling pathways. These pathways might intersect with KIAA1467, indirectly enhancing its activity. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
This compound is a PKC inhibitor. Inhibiting PKC can lead to compensatory responses in signaling networks, potentially enhancing the activity of KIAA1467. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an MEK inhibitor affecting the MAPK/ERK pathway. This modulation may indirectly influence KIAA1467's role in interconnected signaling networks. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3K inhibitor, which impacts the PI3K/Akt pathway. This can indirectly lead to enhanced KIAA1467 activity through related signaling cascades. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum kinase inhibitor. Its broad activity can affect multiple pathways, potentially leading to enhanced KIAA1467 activity through indirect effects. | ||||||