KIAA1107 Inhibitors
The class of chemicals known as KIAA1107 Inhibitors comprises a diverse array of compounds that influence signaling pathways and cellular processes related to the KIAA1107 protein. These inhibitors act through indirect mechanisms, targeting key regulators or pathways associated with KIAA1107 activity. For instance, A-769662 and AICAR indirectly inhibit KIAA1107 by activating AMPK, which can subsequently impact cellular processes dependent on KIAA1107 for enhanced metabolic activity. LY-294002 activates PI3K, influencing downstream pathways related to KIAA1107 activity. Forskolin, GW5074, T0901317, and GW3965 activate various signaling components, such as adenylate cyclase, c-Raf, and LXRs, which intersect with cellular processes governed by KIAA1107.
Additionally, 17-AAG activates Hsp90, playing a role in protein folding and stability, indirectly affecting KIAA1107. SB431542 activates TGF-β receptors, modulating pathways associated with KIAA1107-mediated processes. Retinoic acid and Fasudil activate Retinoic Acid Receptors and ROCK, respectively, impacting gene expression and cytoskeletal dynamics, both influencing cellular functions associated with KIAA1107. Sodium butyrate, as an HDAC inhibitor, modulates chromatin structure, potentially altering gene expression patterns and indirectly affecting KIAA1107 activity. This class of inhibitors, through their diverse modes of indirect action, offers a comprehensive approach to studying and understanding the regulatory mechanisms and functional roles of KIAA1107 in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A-769662 activates AMP-activated protein kinase (AMPK), indirectly inhibiting KIAA1107 by modulating cellular energy status. As AMPK activation leads to energy conservation, it can downregulate pathways dependent on KIAA1107 for enhanced metabolic activity. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR is a precursor to AMP and activates AMPK. By elevating intracellular AMP levels, it stimulates AMPK, triggering a cascade of events that can indirectly inhibit KIAA1107, as AMPK is known to regulate cellular processes associated with KIAA1107 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, leading to increased cAMP levels. This can indirectly inhibit KIAA1107, as cAMP is involved in various signaling pathways that intersect with the functions of KIAA1107. | ||||||
GW 5074 | 220904-83-6 | sc-200639 sc-200639A | 5 mg 25 mg | $106.00 $417.00 | 10 | |
GW5074 activates c-Raf, a kinase involved in the MAPK/ERK pathway. Indirectly, this activation can impact KIAA1107, as the MAPK/ERK pathway intersects with cellular processes where KIAA1107 is active. | ||||||
GW3965 | 405911-09-3 | sc-490151 sc-490151A sc-490151B | 10 mg 50 mg 1 g | $260.00 $872.00 $1637.00 | ||
Similar to T0901317, GW3965 is an LXR activator. Its influence on lipid metabolism and related pathways can indirectly impact KIAA1107, which may be involved in cellular processes influenced by lipid metabolism. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $66.00 $153.00 | 16 | |
17-AAG activates Heat Shock Protein 90 (Hsp90), a chaperone protein. Indirectly, Hsp90 activation can affect KIAA1107, as chaperones play a role in protein folding and stability, influencing the cellular processes where KIAA1107 may be involved. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB431542 activates TGF-β receptors, influencing the TGF-β signaling pathway. As KIAA1107 may be associated with TGF-β-mediated processes, the activation of TGF-β receptors can indirectly modulate the activity of KIAA1107. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid activates Retinoic Acid Receptors (RARs), influencing gene expression. Indirectly, RAR activation can impact KIAA1107, as it may regulate genes or pathways associated with the cellular functions governed by KIAA1107. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate inhibits histone deacetylases (HDACs), affecting chromatin structure and gene expression. By modulating gene expression patterns, sodium butyrate can indirectly influence the activity of KIAA1107, whose functions may be regulated by epigenetic mechanisms. | ||||||