KIAA0100 inhibitors represent a class of chemical compounds designed to target and inhibit the activity of the KIAA0100 protein, a relatively lesser-known protein encoded by the KIAA0100 gene. The exact function of KIAA0100 is still being explored, but it is believed to play roles in cellular regulation and signaling pathways. Inhibitors of KIAA0100 are structured to specifically bind to this protein, disrupting its normal interactions within the cell. This disruption can lead to alterations in various cellular processes, including signal transduction, protein-protein interactions, and regulatory mechanisms that depend on KIAA0100's functional role within the cell.
KIAA0100 inhibitors are crafted to exhibit high specificity and affinity for their target protein, minimizing interference with other cellular components. These inhibitors are often synthesized through rational drug design or discovered via screening methods that identify compounds capable of selectively binding to KIAA0100. The structure of KIAA0100 inhibitors can vary, but they typically incorporate functional groups that allow them to effectively interact with key domains of the KIAA0100 protein. Key design considerations include optimizing the molecular size, shape, charge distribution, and hydrophobic or hydrophilic properties of the inhibitors to ensure they achieve maximum binding efficacy. Structural studies of KIAA0100 and its inhibitors are often used to refine the binding characteristics of these compounds, ensuring they are both selective and potent in modulating the protein's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, a kinase involved in cell growth and protein synthesis, which may affect proteins regulated by these pathways. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can affect multiple signaling pathways, possibly altering the function of proteins like KIAA0100. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Stabilizes microtubules, potentially altering cell cycle and division processes that could indirectly affect KIAA0100's function if it is involved in these processes. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Inhibits cyclin-dependent kinases (CDKs), which are key regulators of the cell cycle, potentially affecting proteins that interact with the cell cycle. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can lead to the accumulation of proteins and may affect proteins that are normally degraded by the proteasome. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, which is involved in signaling pathways that regulate cell growth and survival, potentially affecting proteins modulated by these pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which is involved in stress and inflammatory responses, potentially affecting proteins regulated by JNK signaling. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Inhibits MEK1/2, which are upstream of ERK in the MAPK pathway, potentially affecting proteins modulated by MAPK signaling. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K and affects various cellular processes, possibly altering the function of proteins that are part of PI3K pathways. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein transport by inhibiting the exchange of protein ADP-ribosylation factor, potentially affecting proteins involved in vesicle-mediated transport. | ||||||