Date published: 2025-11-26

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KIAA0100 Inhibitors

KIAA0100 inhibitors represent a class of chemical compounds designed to target and inhibit the activity of the KIAA0100 protein, a relatively lesser-known protein encoded by the KIAA0100 gene. The exact function of KIAA0100 is still being explored, but it is believed to play roles in cellular regulation and signaling pathways. Inhibitors of KIAA0100 are structured to specifically bind to this protein, disrupting its normal interactions within the cell. This disruption can lead to alterations in various cellular processes, including signal transduction, protein-protein interactions, and regulatory mechanisms that depend on KIAA0100's functional role within the cell.

KIAA0100 inhibitors are crafted to exhibit high specificity and affinity for their target protein, minimizing interference with other cellular components. These inhibitors are often synthesized through rational drug design or discovered via screening methods that identify compounds capable of selectively binding to KIAA0100. The structure of KIAA0100 inhibitors can vary, but they typically incorporate functional groups that allow them to effectively interact with key domains of the KIAA0100 protein. Key design considerations include optimizing the molecular size, shape, charge distribution, and hydrophobic or hydrophilic properties of the inhibitors to ensure they achieve maximum binding efficacy. Structural studies of KIAA0100 and its inhibitors are often used to refine the binding characteristics of these compounds, ensuring they are both selective and potent in modulating the protein's activity.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Inhibits mTOR, a kinase involved in cell growth and protein synthesis, which may affect proteins regulated by these pathways.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

A potent kinase inhibitor that can affect multiple signaling pathways, possibly altering the function of proteins like KIAA0100.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

Stabilizes microtubules, potentially altering cell cycle and division processes that could indirectly affect KIAA0100's function if it is involved in these processes.

Roscovitine

186692-46-6sc-24002
sc-24002A
1 mg
5 mg
$92.00
$260.00
42
(2)

Inhibits cyclin-dependent kinases (CDKs), which are key regulators of the cell cycle, potentially affecting proteins that interact with the cell cycle.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

A proteasome inhibitor that can lead to the accumulation of proteins and may affect proteins that are normally degraded by the proteasome.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

Inhibits PI3K, which is involved in signaling pathways that regulate cell growth and survival, potentially affecting proteins modulated by these pathways.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits JNK, which is involved in stress and inflammatory responses, potentially affecting proteins regulated by JNK signaling.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

Inhibits MEK1/2, which are upstream of ERK in the MAPK pathway, potentially affecting proteins modulated by MAPK signaling.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Inhibits PI3K and affects various cellular processes, possibly altering the function of proteins that are part of PI3K pathways.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$30.00
$52.00
$122.00
$367.00
25
(3)

Disrupts protein transport by inhibiting the exchange of protein ADP-ribosylation factor, potentially affecting proteins involved in vesicle-mediated transport.