KIAA0100 activators are chemical compounds that interact with the protein encoded by the KIAA0100 gene, a gene that has been identified through large-scale cDNA sequencing projects aimed at discovering novel proteins. The exact biological function of the KIAA0100 protein is not completely understood, but it is known to be involved in cellular processes that are essential for the maintenance of cellular homeostasis. KIAA0100 activators influence the activity of this protein by binding to it or by modulating its expression, thereby affecting its role within the cell. The molecular mechanisms by which these activators exert their action can vary, and may include altering the protein's conformation, affecting its stability, or influencing its interactions with other cellular components.
The development and characterization of KIAA0100 activators are rooted in the field of biochemistry and molecular biology, where the detailed study of protein functions and their regulatory mechanisms is a central focus. These activators are typically identified through high-throughput screening methods, where libraries of chemical compounds are tested for their ability to modulate the function of KIAA0100. Once identified, activators undergo further analysis to determine their specificity, efficacy, and the nature of their interaction with the KIAA0100 protein. Structural biology techniques such as X-ray crystallography or NMR spectroscopy can be used to visualize the interaction at an atomic level, providing insights into the binding sites and the molecular changes induced by the activator.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor could upregulate KIAA0100 expression by promoting demethylation of the gene's promoter, enhancing its transcriptional activity. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a potent histone deacetylase inhibitor, Trichostatin A may increase the acetylation of histones, thereby stimulating the transcription of KIAA0100. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate may induce expression of KIAA0100 by increasing histone acetylation, contributing to a more relaxed chromatin structure and active gene transcription. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid might induce KIAA0100 transcription by activating its nuclear receptors, which bind to retinoic acid response elements in the genome. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
As a primary female sex hormone, β-Estradiol could stimulate KIAA0100 expression through estrogen receptor-mediated activation of gene transcription. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
This synthetic glucocorticoid could upregulate KIAA0100 by engaging glucocorticoid receptors that interact with glucocorticoid response elements in target genes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride might enhance Wnt signaling, which could lead to the transcriptional activation of KIAA0100 as part of a broader gene expression alteration. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
By inhibiting N-linked glycosylation, Tunicamycin may induce a stress response that includes the upregulation of KIAA0100 as a protective cellular mechanism. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin can lead to increased cytosolic calcium levels and endoplasmic reticulum stress, potentially prompting the upregulation of KIAA0100 to manage cellular stress. | ||||||