KCNQ2 Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ICA 069673 | 582323-16-8 | sc-362745 sc-362745A | 10 mg 50 mg | $159.00 $645.00 | ||
ICA 069673 acts as a selective modulator of KCNQ2 channels, exhibiting unique binding characteristics that enhance channel stability. Its interaction profile is marked by specific electrostatic and van der Waals forces, which influence the conformational dynamics of the channel. The compound's kinetic behavior is notable, as it alters the activation and deactivation rates, thereby fine-tuning ion permeability. This specificity allows for precise manipulation of neuronal excitability without affecting other ion channels. | ||||||
Flupirtine Maleate | 75507-68-5 | sc-218512 | 10 mg | $103.00 | 1 | |
Flupirtine, a relative of retigabine, is also thought to activate KCNQ2 channels. While its primary mechanism is not fully understood, its believed to enhance KCNQ2 channel activity, contributing to its analgesic properties. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc modulates various ion channels, including potassium channels. While its direct effect on KCNQ2 is not fully established, its possible that zinc can influence KCNQ2 channel activity indirectly through its general ion channel modulating properties. | ||||||
Bupivacaine hydrochloride | 18010-40-7 | sc-252524 sc-252524A sc-252524B sc-252524C | 1 g 5 g 50 g 100 g | $104.00 $171.00 $785.00 $1413.00 | ||
Bupivacaine is a local anesthetic known to block various ion channels. It may have an indirect modulatory effect on KCNQ2 channels as part of its broader ion channel-blocking profile, although this is not its primary action. | ||||||
5,5-Diphenyl Hydantoin | 57-41-0 | sc-210385 | 5 g | $70.00 | ||
Phenytoin, an anticonvulsant, affects sodium channels but may also have indirect effects on potassium channels like KCNQ2, contributing to its overall anticonvulsant properties. | ||||||
Carbamazepine | 298-46-4 | sc-202518 sc-202518A | 1 g 5 g | $33.00 $71.00 | 5 | |
Carbamazepine, primarily a sodium channel blocker, might influence KCNQ2 activity indirectly through its broader effects on neuronal excitability and ion channel modulation. | ||||||
Amitriptyline Hydrochloride | 549-18-8 | sc-210801 | 1 g | $200.00 | ||
Amitriptyline, an antidepressant, has complex actions on ion channels. Its indirect effects on KCNQ2 channels, while not clearly defined, may contribute to its overall pharmacological profile, particularly in modulating neuronal excitability. | ||||||
Lamotrigine | 84057-84-1 | sc-201079 sc-201079A | 10 mg 50 mg | $120.00 $486.00 | 1 | |
Lamotrigine, an anticonvulsant, primarily acts on sodium channels, but it may also affect KCNQ2 activity indirectly through its broader effects on neuronal excitability. | ||||||
Citalopram, Hydrobromide Salt | 59729-32-7 | sc-201123 sc-201123A | 10 mg 50 mg | $110.00 $442.00 | 4 | |
Citalopram, an SSRI antidepressant, can have broad effects on neuronal ion channels. Its potential indirect influence on KCNQ2 channels may be part of its overall effect on neuronal excitability, although this is not its primary mechanism of action. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine, a CNS stimulant, influences neuronal excitability. While its direct effect on KCNQ2 is not established, it may have an indirect modulatory effect on these channels as part of its broader impact on neuronal ion channels and signaling. | ||||||