Molecular structure of Citalopram, Hydrobromide Salt, CAS Number: 59729-32-7
Citalopram, Hydrobromide Salt (CAS 59729-32-7)
See product citations (4)
Application:
Citalopram, Hydrobromide Salt is a selective inhibitor of the 5-hydroxytryptamine transporter
CAS Number:
59729-32-7
Purity:
98%
Molecular Weight:
405.30
Molecular Formula:
C20H22BrFN2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Citalopram, Hydrobromide Salt is a selective inhibitor of the ST (5-hydroxytryptamine transporter) (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavior.
Citalopram, Hydrobromide Salt (CAS 59729-32-7) References
- Plasma membrane monoamine transporters: structure, regulation and function. | Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
- The effect of citalopram on gene expression profile of Alzheimer lymphocytes. | Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
- The effect of citalopram hydrobromide on 5-HT2A receptors in the impulsive-aggressive dog, as measured with 123I-5-I-R91150 SPECT. | Peremans, K., et al. 2005. Eur J Nucl Med Mol Imaging. 32: 708-16. PMID: 15739093
- Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study. | Neubauer, HA., et al. 2006. Mol Pharmacol. 69: 1242-50. PMID: 16434615
- Development and application of spectrophotometric methods for the determination of citalopram hydrobromide in dosage forms. | Raza, A. 2006. Chem Pharm Bull (Tokyo). 54: 432-4. PMID: 16595940
- Isolation and characterization of degradation products of citalopram and process-related impurities using RP-HPLC. | Rao, RN., et al. 2008. J Sep Sci. 31: 1729-38. PMID: 18481321
- Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms. | Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
- Synthesis of molecularly imprinted polymer as a sorbent for solid phase extraction of citalopram from human serum and urine. | Abdouss, M., et al. 2012. J Mater Sci Mater Med. 23: 1543-52. PMID: 22484836
- Utility of eosin Y as a complexing reagent for the determination of citalopram hydrobromide in commercial dosage forms by fluorescence spectrophotometry. | Azmi, SN., et al. 2015. Luminescence. 30: 1352-9. PMID: 25829234
- Citalopram Induces Reproductive Toxicity in Male Rats. | Ilgin, S., et al. 2017. Birth Defects Res. 109: 475-485. PMID: 28398617
- Micellar liquid chromatographic method for the simultaneous determination of citalopram hydrobromide with its two demethylated metabolites. Utility as a diagnostic tool in forensic toxicology. | El Sherbiny, D. and Wahba, MEK. 2019. J Pharm Biomed Anal. 164: 173-180. PMID: 30390559
- Development of bioanalytical HPLC method for simultaneous determination of the antialzhiemer, donepezil hydrochloride and the antidepressant, citalopram hydrobromide in raw materials, spiked human plasma and tablets dosage form. | Ragab, GH. and Bahgat, EA. 2019. Ann Pharm Fr. 77: 112-120. PMID: 30528254
- Making Sense of Life-History Effects of the Antidepressant Citalopram in the Copepod Nitocra spinipes Using a Bioenergetics Model. | Koch, J. and De Schamphelaere, KAC. 2021. Environ Toxicol Chem. 40: 1928-1939. PMID: 33760263
Inhibitor of:
ST.Activator of:
KCNQ2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Citalopram, Hydrobromide Salt, 10 mg | sc-201123 | 10 mg | $108.00 | |||
Citalopram, Hydrobromide Salt, 50 mg | sc-201123A | 50 mg | $433.00 |