Date published: 2026-1-22

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IRS-2 Antibodies

Santa Cruz Biotechnology offers a broad range of IRS-2 Antibodies for research focused on understanding the insulin signaling pathway. IRS-2 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IRS-2, or Insulin Receptor Substrate 2, plays a critical role in mediating the effects of insulin and insulin-like growth factors, influencing cellular processes such as glucose metabolism, cell growth, and differentiation. The involvement of IRS-2 in metabolic disorders, including obesity and type 2 diabetes, makes it a significant target for therapeutic research. Researchers investigating IRS-2 can uncover crucial information about insulin signaling pathways and their relationship to various diseases. Understanding IRS-2 function and regulation provides valuable insights into metabolic disease mechanisms and potential therapeutic approaches. The molecular characterization of IRS-2 continues to reveal new aspects of insulin signaling and cellular regulation. Santa Cruz Biotechnology monoclonal antibodies for IRS-2 support researchers worldwide in advancing our understanding of metabolic diseases and potential treatments.

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IRS-2 Antibodies

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IRS-2 Antibody (B-5)

sc-390761mouse IgG1 κ1293-1321 (m)WB, IP, IF, ELISAm, r, h
11
(8)

IRS-2 CRISPR Knockout, HDR and Double Nickase Plasmids

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IRS-2 CRISPR/Cas9 KO Plasmid (h)

sc-400474hGene KnockoutGFP0
(0)

IRS-2 HDR Plasmid (h2)

sc-400474-HDR-2hHomology Directed RepairPuromycin0
(0)

IRS-2 Double Nickase Plasmid (h)

sc-400474-NIChGene KnockoutPuromycin0
(0)

IRS-2 Double Nickase Plasmid (h2)

sc-400474-NIC-2hGene KnockoutPuromycin0
(0)

IRS-2 CRISPR/Cas9 KO Plasmid (m)

sc-436438mGene KnockoutGFP0
(0)

IRS-2 HDR Plasmid (m)

sc-436438-HDRmHomology Directed RepairPuromycin0
(0)

IRS-2 CRISPR Activation Products

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IRS-2 CRISPR Activation Plasmid (h)

sc-400474-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRS-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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IRS-2 siRNA (h)

sc-29378hGene SilencingN/A
5
(0)

IRS-2 shRNA Plasmid (h)

sc-29378-SHhGene SilencingPuromycin
5
(0)

IRS-2 shRNA (h) Lentiviral Particles

sc-29378-VhGene SilencingPuromycin
5
(0)

IRS-2 siRNA (m)

sc-35714mGene SilencingN/A0
(0)

IRS-2 shRNA Plasmid (m)

sc-35714-SHmGene SilencingPuromycin0
(0)

IRS-2 shRNA (m) Lentiviral Particles

sc-35714-VmGene SilencingPuromycin0
(0)

IRS-2 siRNA (r)

sc-155988rGene SilencingN/A
1
(0)

IRS-2 shRNA Plasmid (r)

sc-155988-SHrGene SilencingPuromycin
1
(0)

IRS-2 shRNA (r) Lentiviral Particles

sc-155988-VrGene SilencingPuromycin
1
(0)