Irgm2 Activators
The chemical class termed Irgm2 Activators encompasses a diverse range of compounds, each with unique molecular structures and mechanisms of action, yet they are unified by their potential to influence the activity of the protein Irgm2 indirectly. This group includes molecules like Forskolin, which operates through the elevation of cAMP levels, potentially affecting Irgm2 by modulating immune signaling pathways. Phorbol 12-myristate 13-acetate (PMA), another member of this class, activates protein kinase C, a key player in immune response regulation, thereby potentially affecting Irgm2 activity via downstream signaling cascades. Antioxidants like Resveratrol, known for influencing cellular redox states, might also impact Irgm2 activity, considering the protein's involvement in immune-related pathways. Compounds such as Curcumin and Epigallocatechin gallate (EGCG) are included due to their roles in affecting NF-κB signaling and multiple signaling pathways, respectively, which could bear relevance to the regulation of Irgm2.
Moreover, this class includes biochemicals like Spermine, which, through its role in modulating cellular signaling and oxidative stress responses, may indirectly influence Irgm2 activity. Sodium butyrate, a compound known for its influence on histone deacetylases and gene expression modulation, also falls within this category, potentially impacting Irgm2-related pathways. The class further includes Dexamethasone, a compound that modulates inflammatory pathways and might affect Irgm2 activity indirectly. Similarly, Lithium chloride, known for its influence on GSK-3β signaling, Metformin, an activator of AMP-activated protein kinase (AMPK), Rapamycin, an mTOR inhibitor, and Sulforaphane, which modulates Nrf2-related oxidative stress responses, are part of this group. Each of these compounds, through their respective pathways and mechanisms, contributes to the dynamic nature of this chemical class, underscoring the complex interplay of cellular signaling pathways and their potential impact on Irgm2.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels, which can modulate immune signaling pathways potentially influencing Irgm2 activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C, which plays a role in modulating immune responses and could affect Irgm2 activity through downstream signaling cascades. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
As an antioxidant, Resveratrol can influence redox states in cells, which may affect the signaling pathways involving Irgm | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin affects NF-κB signaling, which is crucial in immune response regulation and could indirectly influence Irgm2 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a polyphenol in green tea, can modulate several signaling pathways, potentially impacting the regulatory mechanisms associated with Irgm | ||||||
Spermine | 71-44-3 | sc-212953A sc-212953 sc-212953B sc-212953C | 1 g 5 g 25 g 100 g | $60.00 $192.00 $272.00 $883.00 | 1 | |
Spermine, a polyamine, can modulate cellular signaling and oxidative stress responses, which may indirectly influence Irgm2 activity. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
This short-chain fatty acid affects histone deacetylases and can modulate gene expression, possibly impacting pathways in which Irgm2 is involved. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid, Dexamethasone can modulate inflammatory pathways and may indirectly affect Irgm2 activity through these mechanisms. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences GSK-3β signaling, which is involved in various cellular processes including immune response, potentially impacting Irgm2 activity. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin activates AMP-activated protein kinase (AMPK), which is involved in cellular energy regulation and might influence pathways related to Irgm2 activity. | ||||||