Inhibin β-B Activators
Inhibin β-B activators belong to a chemical class of compounds that interact with Inhibin β-B, a protein primarily associated with reproductive and endocrine functions in vertebrates. Inhibin β-B is a subunit of the inhibin complex, which also consists of an α subunit. These complexes are produced in various tissues, with a significant presence in the ovaries and testes, where they play a vital role in regulating the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary gland. The primary function of Inhibin β-B is to inhibit the production and release of FSH, a hormone that plays a key role in the maturation of ovarian follicles and spermatogenesis in males. Inhibin β-B activators are designed to modulate the activity of this protein, influencing the delicate balance of reproductive and endocrine processes.
The mechanism of action of Inhibin β-B activators typically involves their interaction with Inhibin β-B, leading to changes in its conformation or stability. By doing so, these compounds may enhance or reduce the inhibitory effect of Inhibin β-B on FSH production, thereby influencing the levels of FSH circulating in the body. This, in turn, can have downstream effects on the reproductive and endocrine systems, which are essential for the regulation of fertility and other related physiological processes. Researchers continue to explore the molecular interactions and effects associated with Inhibin β-B activators, contributing to our understanding of the intricate mechanisms governing reproduction and endocrine regulation in vertebrates.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
A selective inhibitor of ALK5, ALK4, and ALK7, which indirectly upregulates activin signaling, potentially influencing Inhibin β-B activity. | ||||||
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
A potent ALK2 and ALK3 inhibitor, indirectly modulating activin signaling pathways linked to Inhibin β-B. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
An inhibitor of ALK5, ALK4, and ALK7, similar to SB-431542, it can indirectly impact Inhibin β-B through activin signaling modulation. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $77.00 $153.00 $219.00 $663.00 $1248.00 $4382.00 $7850.00 | 8 | |
An ALK5 inhibitor that may indirectly affect Inhibin β-B function by altering activin/TGF-β signaling pathways. | ||||||
EW-7197 | 1352608-82-2 | sc-507465 | 5 mg | $345.00 | ||
A selective inhibitor of ALK5, indirectly modulating Inhibin β-B activity through activin/TGF-β signaling pathways. | ||||||
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $107.00 $156.00 | 4 | |
Another ALK5 inhibitor that can indirectly influence the activity of Inhibin β-B through the activin/TGF-β pathway. | ||||||
DMH-1 | 1206711-16-1 | sc-361171 sc-361171B sc-361171A sc-361171C | 10 mg 25 mg 50 mg 100 mg | $213.00 $318.00 $632.00 $1047.00 | 2 | |
A selective ALK2 inhibitor, impacting signaling pathways associated with Inhibin β-B. | ||||||
SB-505124 | 694433-59-5 | sc-362794 sc-362794A | 10 mg 50 mg | $327.00 $1377.00 | 2 | |
Inhibits ALK4, ALK5, and ALK7, indirectly modulating Inhibin β-B activity through activin/TGF-β signaling. | ||||||
TGF-β RI Kinase Inhibitor VIII | 356559-20-1 | sc-203295 | 2 mg | $100.00 | 2 | |
An ALK5 inhibitor, indirectly influencing Inhibin β-B activity via activin/TGF-β signaling pathways. | ||||||
K02288 | 1431985-92-0 | sc-488981 | 5 mg | $330.00 | ||
Targets ALK2, ALK3, and ALK6, indirectly affecting Inhibin β-B related pathways. | ||||||