IleRS Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pseudomonic Acid | 12650-69-0 | sc-202299 | 25 mg | $173.00 | 1 | |
Pseudomonic Acid functions as a selective inhibitor of bacterial protein synthesis, exhibiting a unique mechanism of action through its interaction with the ribosomal peptidyl transferase center. This compound forms stable complexes with the ribosome, disrupting peptide bond formation. Its distinct molecular structure allows for specific binding, leading to altered reaction kinetics that inhibit bacterial growth. The compound's hydrophobic regions enhance its affinity for ribosomal sites, influencing translational fidelity. | ||||||
Halofuginone | 55837-20-2 | sc-507290 | 100 mg | $1740.00 | ||
An inhibitor of prolyl-tRNA synthetase; while not specific to IleRS, it disrupts aminoacyl-tRNA synthetase activity and can indirectly affect IleRS function. | ||||||
Reveromycin A | 134615-37-5 | sc-202314 sc-202314A | 100 µg 500 µg | $188.00 $426.00 | 1 | |
Reveromycin A is characterized by its ability to modulate cellular signaling pathways through selective inhibition of protein synthesis. It interacts with ribosomal RNA, leading to conformational changes that disrupt the normal translation process. This compound exhibits unique binding dynamics, allowing it to stabilize intermediates in the ribosomal assembly, thereby affecting the kinetics of peptide elongation. Its distinct hydrophobic and polar regions facilitate targeted interactions, enhancing its specificity in molecular recognition. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known for its antimalarial activity, it can affect protein synthesis, potentially influencing IleRS activity indirectly. | ||||||
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $62.00 $92.00 $265.00 $409.00 $622.00 | 6 | |
A broad-spectrum antibiotic that inhibits protein synthesis in bacteria; could provide insights into mechanisms indirectly affecting IleRS. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Mimics an aminoacyl-tRNA and causes premature chain termination during protein synthesis, potentially affecting IleRS activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, affecting signaling pathways involved in protein synthesis, possibly influencing IleRS activity. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis by interfering with the translocation step, potentially affecting IleRS indirectly. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
A protein synthesis inhibitor that can interfere with peptide elongation, possibly influencing IleRS activity. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $56.00 $240.00 $815.00 $1305.00 | 4 | |
An antibiotic that inhibits bacterial protein synthesis, potentially offering mechanisms to indirectly affect IleRS. | ||||||