Pseudomonic Acid (CAS 12650-69-0)
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Pseudomonic Acid, also known as mupirocin, is an antibiotic that can be found in Pseudomonas fluorescens which strongly inhibits protein and RNA synthesis. Inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. This enzyme is for the synthesis of bacterial proteins by attaching the amino acid isoleucine to its corresponding tRNA. By inhibiting this enzyme, Pseudomonic Acid effectively stops the production of proteins necessary for bacterial growth and replication, leading to the bacteria′s death. Pseudomonic Acid also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.
Pseudomonic Acid (CAS 12650-69-0) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pseudomonic Acid, 25 mg | sc-202299 | 25 mg | $173.00 |