IGSF4D inhibitors are a class of chemical compounds that target the immunoglobulin superfamily member 4D (IGSF4D), a cell adhesion molecule that belongs to the broader family of immunoglobulin-like proteins. These proteins are known for their role in mediating various cellular processes, including cell-cell adhesion, signal transduction, and cellular communication. IGSF4D is predominantly expressed in specific tissues, such as the brain and immune cells, where it contributes to the structural and functional integrity of these tissues. The inhibition of IGSF4D can disrupt normal cellular communication and adhesion, leading to altered cellular responses. This type of inhibition may interfere with interactions between cells and the extracellular matrix, ultimately affecting the overall behavior and functionality of cells in different environments.
The molecular structure of IGSF4D inhibitors generally involves elements that allow for the specific binding to the IGSF4D protein, often involving interactions with key functional domains of the molecule. These interactions may occur through hydrogen bonding, hydrophobic interactions, or other forces that enable strong and selective binding. The design and discovery of IGSF4D inhibitors typically require an understanding of the protein's structure, especially its extracellular domains involved in adhesion and signaling. By targeting these domains, IGSF4D inhibitors can modulate the activity of the protein, thus providing insights into its role in cellular processes and enabling researchers to study its biological functions in greater detail.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Rho kinase inhibitor; CADM2's signaling might be affected given Rho's role in adhesion and cell migration. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
By inhibiting the ERK pathway, it can indirectly influence CADM2-associated signaling. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $179.00 $307.00 $455.00 $924.00 $1689.00 | 7 | |
Inhibits non-muscle myosin II, which is crucial for cell adhesion and might impact CADM2 functionality. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that might modulate CADM2's functionalities since PI3K is involved in cell signaling. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Src family kinase inhibitor that can modulate signaling pathways potentially associated with CADM2. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
CDC42 inhibitor, affecting cell adhesion and migration which might indirectly modulate CADM2 activities. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Tyrosine kinase inhibitor that might influence CADM2 functionalities due to its role in signaling modulation. | ||||||
Manumycin A | 52665-74-4 | sc-200857 sc-200857A | 1 mg 5 mg | $215.00 $622.00 | 5 | |
Ras inhibitor that could interfere with signaling pathways related to CADM2. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAPK, a key signaling molecule, potentially affecting pathways where CADM2 plays a role. | ||||||