IgHg Inhibitors
The heavy chain gamma determines the class of the immunoglobulin, such as IgG, IgA, or IgM. It could be speculated that these compounds are designed to selectively target and inhibit the function of the immunoglobulin heavy chain gamma.
Chemically, IgHg Inhibitors would likely be structured to interact specifically with the heavy chain gamma, potentially influencing its role in antibody production or immune response regulation. These inhibitors might possess distinct molecular features aimed at binding to particular regions of the heavy chain gamma, thereby modulating its activity. The development of such inhibitors could be rooted in a broader scientific interest in understanding the intricacies of the immune system and its components. The class of IgHg Inhibitors, if it were to exist, would likely contribute to the exploration of immune system dynamics, providing researchers with valuable tools to dissect the molecular mechanisms associated with immunoglobulin function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate is an antimetabolite that can inhibit the proliferation of rapidly dividing cells, including B cells responsible for immunoglobulin production. | ||||||
Chlorambucil | 305-03-3 | sc-204682 sc-204682A | 250 mg 1 g | $51.00 $120.00 | 3 | |
Chlorambucil alkylates DNA, and while used in certain hematologic malignancies, it may also affect B cell DNA, reducing immunoglobulin synthesis. | ||||||
Cyclophosphamide | 50-18-0 | sc-361165 sc-361165A sc-361165B sc-361165C | 50 mg 100 mg 500 mg 1 g | $76.00 $143.00 $469.00 $775.00 | 18 | |
Cyclophosphamide is a cytotoxic compound that cross-links DNA and can suppress B cell function and thus immunoglobulin production. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $56.00 | 1 | |
Hydroxychloroquine can modulate immune activity and has been shown to reduce B cell activation, which may decrease immunoglobulin levels. | ||||||
Fludarabine | 21679-14-1 | sc-204755 sc-204755A | 5 mg 25 mg | $57.00 $200.00 | 15 | |
Fludarabine is a purine analog that can interfere with DNA synthesis and is known to suppress B cell function, potentially affecting immunoglobulin expression. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $199.00 $173.00 $342.00 $495.00 $690.00 | 1 | |
Azathioprine is an immunosuppressive drug that can reduce the proliferation of B cells and thereby decrease immunoglobulin production. | ||||||
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $36.00 $107.00 | 1 | |
Mycophenolate mofetil inhibits inosine monophosphate dehydrogenase and can suppress B cell proliferation and antibody production. | ||||||
Leflunomide | 75706-12-6 | sc-202209 sc-202209A | 10 mg 50 mg | $20.00 $81.00 | 5 | |
Leflunomide inhibits dihydroorotate dehydrogenase, leading to a reduction in pyrimidine synthesis and can decrease B cell proliferation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor that can induce B cell apoptosis, potentially leading to reduced immunoglobulin production. | ||||||
Lenalidomide | 191732-72-6 | sc-218656 sc-218656A sc-218656B | 10 mg 100 mg 1 g | $49.00 $367.00 $2030.00 | 18 | |
Lenalidomide modulates the immune system and can reduce B cell activity, which may result in decreased production of immunoglobulins. | ||||||