Date published: 2025-11-23

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I kappa B-α Antibodies

Santa Cruz Biotechnology delivers a wide array of I kappa B-α monoclonal antibodies for research focused on understanding the NF-κB signaling pathway. I kappa B-α Antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). I kappa B-α is a critical inhibitor of NF-κB, a transcription factor that plays a vital role in regulating immune responses, inflammation, and cell survival. By sequestering NF-κB in the cytoplasm, I kappa B-α prevents its translocation to the nucleus, thereby modulating gene expression in response to various stimuli. Understanding the dynamics of I kappa B-α is essential for elucidating the mechanisms underlying numerous diseases, including cancer and autoimmune disorders. Researchers can explore protein-protein interactions, cellular localization, and expression patterns of I kappa B-α in different cellular states and conditions. Advanced visualization techniques using fluorescent conjugates enable detailed analysis of I kappa B-α distribution and dynamics in living cells. Comprehensive characterization of I kappa B-α behavior under various experimental conditions helps reveal new aspects of cellular signaling networks. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of cellular signaling pathways and their implications in human health and disease.

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I kappa B-α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

cleaved NFKBIA/IkB alpha Antibody (5D1623)

sc-52900mouse IgG1FL (h)WBh
7
(1)

cleaved NFKBIA/IkB alpha Antibody (4H110)

sc-71291mouse IgG1FL (h)WBh
3
(1)

NFKBIA/IkB alpha Antibody (H-4)

sc-1643mouse IgG1 κFL (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
552
(59)

NFKBIA/IkB alpha Antibody (B-3)

sc-373893mouse IgA2-27 (h)WB, IP, IF, ELISAh
21
(2)

Phospho-Specific I kappa B-α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-NFKBIA/IkB alpha Antibody (B-9)

sc-8404mouse IgG2b κSer 32 (h)WB, IP, IF, IHC(P)m, r, h
518
(50)

p-NFKBIA/IkB alpha Antibody (39A1431)

sc-52943mouse IgG1 κSer 32/36 (h)WBm, r, h
25
(1)

I kappa B-α CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NFKBIA/IkB alpha CRISPR/Cas9 KO Plasmid (h2)

sc-400034-KO-2hGene KnockoutGFP
1
(1)

NFKBIA/IkB alpha HDR Plasmid (h2)

sc-400034-HDR-2hHomology Directed RepairPuromycin
1
(1)

NFKBIA/IkB alpha Double Nickase Plasmid (h)

sc-400034-NIChGene KnockoutPuromycin
1
(1)

NFKBIA/IkB alpha Double Nickase Plasmid (h2)

sc-400034-NIC-2hGene KnockoutPuromycin
1
(1)

NFKBIA/IkB alpha CRISPR/Cas9 KO Plasmid (m)

sc-421878mGene KnockoutGFP0
(0)

NFKBIA/IkB alpha HDR Plasmid (m)

sc-421878-HDRmHomology Directed RepairPuromycin0
(0)

NFKBIA/IkB alpha Double Nickase Plasmid (m)

sc-421878-NICmGene KnockoutPuromycin0
(0)

NFKBIA/IkB alpha Double Nickase Plasmid (m2)

sc-421878-NIC-2mGene KnockoutPuromycin0
(0)

I kappa B-α CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NFKBIA/IkB alpha CRISPR Activation Plasmid (h)

sc-400034-ACThGene ActivationPuro, Blast, Hygro
1
(1)

NFKBIA/IkB alpha CRISPR Activation Plasmid (h2)

sc-400034-ACT-2hGene ActivationPuro, Blast, Hygro
1
(1)

NFKBIA/IkB alpha Lentiviral Activation Particles (h)

sc-400034-LAChGene ActivationPuro, Blast, Hygro
1
(1)

NFKBIA/IkB alpha Lentiviral Activation Particles (h2)

sc-400034-LAC-2hGene ActivationPuro, Blast, Hygro
1
(1)

NFKBIA/IkB alpha CRISPR Activation Plasmid (m)

sc-421878-ACTmGene ActivationPuro, Blast, Hygro0
(0)

NFKBIA/IkB alpha CRISPR Activation Plasmid (m2)

sc-421878-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

NFKBIA/IkB alpha Lentiviral Activation Particles (m)

sc-421878-LACmGene ActivationPuro, Blast, Hygro0
(0)

NFKBIA/IkB alpha Lentiviral Activation Particles (m2)

sc-421878-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

I kappa B-α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NFKBIA/IkB alpha siRNA (h)

sc-29360hGene SilencingN/A
11
(1)

NFKBIA/IkB alpha siRNA (h2)

sc-44265hGene SilencingN/A
1
(0)

NFKBIA/IkB alpha shRNA Plasmid (h)

sc-29360-SHhGene SilencingPuromycin
11
(1)

NFKBIA/IkB alpha shRNA Plasmid (h2)

sc-44265-SHhGene SilencingPuromycin
1
(0)

NFKBIA/IkB alpha shRNA (h) Lentiviral Particles

sc-29360-VhGene SilencingPuromycin
11
(1)

NFKBIA/IkB alpha shRNA (h2) Lentiviral Particles

sc-44265-VhGene SilencingPuromycin
1
(0)

NFKBIA/IkB alpha siRNA (m)

sc-29361mGene SilencingN/A
5
(0)

NFKBIA/IkB alpha shRNA Plasmid (m)

sc-29361-SHmGene SilencingPuromycin
5
(0)

NFKBIA/IkB alpha shRNA (m) Lentiviral Particles

sc-29361-VmGene SilencingPuromycin
5
(0)