cleaved NFKBIA/IkB alpha Antibody (4H110): sc-71291
- cleaved NFKBIA/IkB alpha Antibody (4H110) is a mouse monoclonal IgG1, cited in 3 publications, provided at 100 µg/ml
- raised against synthetic IκB-α of human origin
- recommended for detection of cleaved IκB-α of human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for cleaved NFKBIA/IkB alpha Antibody (4H110). This work is in progress.
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cleaved IκBα Antibody (4H110) is a mouse monoclonal IgG1 antibody that detects cleaved IκBα in human samples through western blotting (WB). Cleaved IκBα plays a crucial role in regulating NF-κB signaling pathway, which controls various cellular processes, including inflammation, immune response, and cell survival. Upon stimulation by pro-inflammatory cytokines or other signals, IκBα is phosphorylated and subsequently degraded, allowing NF-κB dimers, such as p65 and p50, to translocate to the nucleus and activate target genes. This process is vital for proper immune system function and stress response, making cleaved IκBα (4H110) monoclonal antibody essential for understanding various diseases, including cancer and autoimmune disorders. Anti-cleaved IκBα antibody (4H110) provides reliable detection of this post-translationally modified protein, facilitating research into cellular signaling and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cleaved NFKBIA/IkB alpha Antibody (4H110) | sc-71291 | 100 µg/ml | $316.00 |