NFKBIA/IkB alpha Antibody (B-3): sc-373893
- NFKBIA/IkB alpha Antibody (B-3) is a mouse monoclonal IgA κ, cited in 21 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-27 within the N-terminus of IκB-α of human origin
- recommended for detection of IκB-α of human origin by WB, IP, IF and ELISA
- See NFKBIA/IkB alpha (H-4): sc-1643 for NFKBIA/IkB alpha antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NFKBIA/IkB alpha Antibody (B-3). This work is in progress.
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IκB-α Antibody (B-3) is a mouse monoclonal IgA antibody that detects IκB-α in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IκB-α plays a crucial role in the regulation of the NF-κB signaling pathway, which is vital for controlling immune responses, cell proliferation, and survival. By sequestering NF-κB dimers in the cytoplasm, IκB-α prevents their translocation to the nucleus, thereby inhibiting the expression of target genes involved in inflammation and immune responses. The importance of IκB-α′s function is underscored by involvement in various diseases, including cancer and autoimmune disorders, where dysregulation of NF-κB activity can lead to pathological conditions. Additionally, IκB-α undergoes post-translational modifications, such as phosphorylation, which can influence stability and interaction with NF-κB, further highlighting a critical role in cellular signaling. Anti-IκB-α antibody (B-3) is an essential tool for researchers studying the NF-κB pathway and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NFKBIA/IkB alpha Antibody (B-3) | sc-373893 | 200 µg/ml | $316.00 | |||
NFKBIA/IkB alpha (B-3) Neutralizing Peptide | sc-373893 P | 100 µg/0.5 ml | $68.00 |