HSZFP36 inhibitors are a category of chemical compounds designed to target and modulate the activity of HSZFP36, which stands for Heat Shock Zinc Finger Protein 36. HSZFP36 is a protein containing zinc finger domains, which are often involved in DNA binding and transcriptional regulation. While the specific functions of HSZFP36 are still being elucidated, zinc finger proteins like HSZFP36 are known to play essential roles in regulating gene expression, cellular stress responses, and various other cellular processes. Inhibitors of HSZFP36 are developed to interact with this specific protein, influencing its DNA-binding capabilities, interactions with regulatory elements, or its participation in cellular processes where HSZFP36 is involved.
Structurally, HSZFP36 inhibitors are meticulously designed to engage specific regions or binding sites on the HSZFP36 protein. This interaction may disrupt the normal functioning of HSZFP36, affecting its ability to modulate gene expression or its involvement in cellular signaling pathways. The mechanisms by which HSZFP36 inhibitors exert their effects can vary, but their primary purpose is to serve as valuable tools for researchers studying the roles of HSZFP36 in various cellular contexts. Investigating the biochemical and functional aspects of HSZFP36 and its modulation by inhibitors can contribute to a deeper understanding of transcriptional regulation, cellular stress responses, and the broader field of molecular and cellular biology. Ultimately, such research can offer insights into the intricate molecular mechanisms that govern fundamental cellular functions and their regulation by HSZFP36.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor; can influence protein degradation including potentially some zinc finger proteins. | ||||||
3-Deazaneplanocin, HCl salt | 120964-45-6 | sc-351856 sc-351856A sc-351856B | 1 mg 5 mg 10 mg | $251.00 $600.00 $918.00 | 2 | |
Inhibitor of the histone methyltransferase EZH2; might influence chromatin structure and the expression of zinc finger genes. | ||||||
GSK343 | 1346704-33-3 | sc-397025 sc-397025A | 5 mg 25 mg | $148.00 $452.00 | 1 | |
Another EZH2 inhibitor; can influence epigenetic markers and potentially the expression of zinc finger genes. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
NF-κB pathway inhibitor; since some zinc finger proteins play roles in inflammation, it might indirectly affect their function. | ||||||
Stat3 inhibitor V, stattic | 19983-44-9 | sc-202818 sc-202818A sc-202818B sc-202818C sc-202818D sc-202818E sc-202818F | 25 mg 100 mg 250 mg 500 mg 1 g 2.5 g 5 g | $127.00 $192.00 $269.00 $502.00 $717.00 $1380.00 $2050.00 | 114 | |
Inhibits STAT3 activation and dimerization. Some zinc finger proteins are involved in JAK-STAT signaling. | ||||||
β-Catenin/Tcf Inhibitor, FH535 | 108409-83-2 | sc-221398 sc-221398A | 10 mg 50 mg | $178.00 $367.00 | 7 | |
Inhibits Wnt/β-catenin and PPAR signaling. Some zinc finger proteins are involved in these pathways. | ||||||
CDC25 Phosphatase Inhibitor II, NSC 663284 | 383907-43-5 | sc-202987A sc-202987 sc-202987B sc-202987C | 1 mg 5 mg 10 mg 25 mg | $50.00 $236.00 $350.00 $650.00 | 4 | |
Potent inhibitor of Cdc25 dual specificity phosphatases; might influence cell cycle pathways related to zinc finger proteins. | ||||||