Hsp70-3 Inhibitors
Hsp70-3 Inhibitors are a class of compounds that inhibit the expression or activity of the Hsp70-3 protein. Hsp70-3 is a protein that plays a critical role in the cellular response to stress. Hsp70-3 binds to misfolded proteins and helps to refold them or target them for degradation. Hsp70-3 Inhibitors exert their effect by modulating different aspects of Hsp70-3 biology. Some Hsp70-3 Inhibitors, such as small molecule inhibitors, can directly bind to Hsp70-3 and prevent it from interacting with misfolded proteins or from being activated. Other Hsp70-3 Inhibitors, such as gene silencing agents (e.g., siRNA, shRNA), can reduce the expression of Hsp70-3 mRNA or protein.
By modulating Hsp70-3 expression or activity, Hsp70-3 Inhibitors can influence the cellular response to stress and protein folding. It is important to note that Hsp70-3 Inhibitors are a diverse class of compounds with different mechanisms of action. The specific effects of a particular Hsp70-3 Inhibitor will depend on its chemical structure and target. Further research is needed to characterize the different Hsp70-3 Inhibitors and to investigate their potential applications in research and medicine.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
An inorganic compound that induces oxidative stress and activates the heat shock response pathway, leading to increased Hsp70-3 expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
An antibiotic that inhibits N-linked glycosylation and induces ER stress, leading to increased Hsp70-3 expression. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
A reactive oxygen species that induces oxidative stress and activates the heat shock response pathway, leading to increased Hsp70-3 expression. | ||||||
4-Hydroxynonenal | 75899-68-2 | sc-202019 sc-202019A sc-202019B | 1 mg 10 mg 50 mg | $116.00 $642.00 $2720.00 | 25 | |
A lipid peroxidation product that induces oxidative stress and activates the heat shock response pathway, leading to increased Hsp70-3 expression. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
A benzoquinone ansamycin antibiotic that inhibits the binding of Hsp90 to client proteins, leading to increased Hsp70-3 expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A flavonoid that induces the heat shock response pathway and inhibits the degradation of Hsp70-3, leading to increased Hsp70-3 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenol that induces the heat shock response pathway and inhibits the degradation of Hsp70-3, leading to increased Hsp70-3 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A curcuminoid that induces the heat shock response pathway and inhibits the degradation of Hsp70-3, leading to increased Hsp70-3 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A green tea catechin that induces the heat shock response pathway and inhibits the degradation of Hsp70-3, leading to increased Hsp70-3 expression. | ||||||