HSP 75 Inhibitors
The chemical class of HSP 75 Inhibitors encompasses a variety of compounds that can potentially inhibit the function of HSP 75 indirectly by targeting cellular processes and stress response pathways related to mitochondrial function. Compounds like gambogic acid and novobiocin, while targeting other primary proteins or pathways, may have a secondary effect of inhibiting HSP 75 through altered cellular survival pathways. Mitochondrial uncouplers, antimycin A, and oligomycin directly affect mitochondrial function, which can impact HSP 75 activity due to its role in mitochondrial stress response.
Dequalinium chloride and sodium arsenite, by inducing mitochondrial dysfunction and oxidative stress, respectively, can influence HSP 75 activity. Similarly, 2-Deoxy-D-glucose, by inhibiting glycolysis, may cause cellular stress that affects HSP 75 function. Brefeldin A and concanamycin A, through their disruption of cellular homeostasis, might indirectly impact HSP 75. MG132, as a proteasome inhibitor, induces cellular stress, which can potentially influence HSP 75 activity. Staurosporine, a broad-spectrum kinase inhibitor, might affect HSP 75 activity by altering multiple cellular signaling pathways.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Gambogic Acid | 2752-65-0 | sc-200137 sc-200137A sc-200137B sc-200137C sc-200137D | 5 mg 25 mg 100 mg 500 mg 1 g | $85.00 $243.00 $419.00 $720.00 $1230.00 | 5 | |
Known to target several proteins involved in cell survival, it may indirectly inhibit HSP 75 by affecting associated pathways. | ||||||
Novobiocin | 303-81-1 | sc-362034 sc-362034A | 5 mg 25 mg | $96.00 $355.00 | ||
An antibiotic that also acts as an HSP90 inhibitor, potentially impacting HSP 75 function indirectly. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
Disrupts mitochondrial membrane potential, possibly affecting HSP 75 function as part of mitochondrial stress response. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
Inhibits mitochondrial complex III, potentially impacting mitochondrial function and indirectly HSP 75 activity. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
Inhibits mitochondrial ATP synthase, possibly affecting HSP 75 function due to altered mitochondrial dynamics. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor, may cause cellular stress potentially affecting HSP 75 function. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts endoplasmic reticulum-to-Golgi apparatus transport, potentially influencing cellular stress pathways linked to HSP 75. | ||||||
Concanamycin A | 80890-47-7 | sc-202111 sc-202111A sc-202111B sc-202111C | 50 µg 200 µg 1 mg 5 mg | $65.00 $162.00 $650.00 $2550.00 | 109 | |
Inhibits V-ATPase, potentially disrupting cellular homeostasis and indirectly affecting HSP 75. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor, can induce cellular stress potentially impacting HSP 75 activity. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A broad-spectrum kinase inhibitor, might affect several signaling pathways potentially influencing HSP 75 activity. | ||||||