Date published: 2026-3-3

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hornerin Activators

Hornerin Activators constitute a specialized class of chemical compounds or molecules designed or identified with the specific aim of modulating the activity of the hornerin gene. Hornerin, also known as S100A16, is a protein-coding gene found in humans and other organisms. It plays a vital role in the structure and function of the skin, particularly in the epidermis. Hornerin is involved in the formation and maintenance of the cornified envelope, a critical component of the skin's barrier function.

The study of hornerin activators is significant because it provides researchers with a means to delve into the precise role of the hornerin gene in skin physiology and molecular mechanisms related to epidermal barrier function and integrity. Activation of hornerin can offer valuable insights into its potential involvement in processes such as the assembly of structural proteins within the skin's outermost layer and its response to environmental stressors. By manipulating the activity of hornerin through these activators, scientists aim to gain a deeper understanding of the intricate molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of skin biology and its essential role in providing protection to the body. Consequently, hornerin activators serve as indispensable tools for researchers dedicated to unraveling the complex molecular mechanisms that govern skin health and the specific functions played by individual genes in these processes, particularly within the context of skin barrier formation and maintenance.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Activates nuclear receptors, potentially enhancing gene expression tied to epidermal differentiation, including hornerin.

Calcipotriol

112965-21-6sc-203537
sc-203537A
10 mg
50 mg
$203.00
$832.00
4
(1)

A vitamin D analog that could affect gene expression through the vitamin D receptor, possibly influencing hornerin expression.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

May have antifungal properties and could influence skin barrier gene expression as part of its activity.

Imiquimod

99011-02-6sc-200385
sc-200385A
100 mg
500 mg
$67.00
$284.00
6
(1)

Known to modulate immune responses and could affect keratinocyte differentiation and related gene expression.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Has been shown to affect multiple cellular signaling pathways, which might indirectly influence hornerin expression.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$44.00
$66.00
$204.00
$831.00
6
(1)

A form of vitamin B3 that can influence cellular metabolism and differentiation, potentially affecting hornerin levels.

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$37.00
$104.00
$580.00
$1196.00
10
(1)

A fatty acid that impacts skin barrier function, which could lead to changes in expression of barrier-related proteins like hornerin.

Glycolic acid solution

79-14-1sc-215102
sc-215102A
25 g
500 g
$38.00
$60.00
(0)

An alpha-hydroxy acid that might influence skin cell turnover and differentiation, potentially modulating hornerin expression.

(+)-α-Tocopherol

59-02-9sc-214454
sc-214454A
sc-214454B
sc-214454C
10 g
25 g
100 g
1 kg
$43.00
$62.00
$141.00
$430.00
(1)

An antioxidant that may protect skin cells and influence gene expression relevant to skin barrier function.

Selenium

7782-49-2sc-250973
50 g
$62.00
1
(1)

Used in certain topical applications, could induce a cellular response that affects the expression of skin-related genes.